STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Arch_0556Dihydroxyacetone kinase, L subunit; COGs: COG2376 Dihydroxyacetone kinase; InterPro IPR004007:IPR012737; KEGG: car:cauri_1454 dihydroxyacetone kinase; PFAM: Dak phosphatase; SPTR: A7BCU2 Putative uncharacterized protein; TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: DAK2 domain; TIGRFAM: dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. (202 aa)    
Predicted Functional Partners:
Arch_1122
Dihydroxyacetone kinase, phosphotransfer subunit; COGs: COG3412 conserved hypothetical protein; InterProIPR000032:IPR004701:IPR012844:IPR005698:IPR 001020; KEGG: ecm:EcSMS35_4856 phosphoenolpyruvate-protein phosphotransferase PtnE; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; SPTR: D0YPG5 PTS-dependent dihydroxyacetone kinase, DhaM subunit; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; PFAM: PTS system fructose IIA component; PTS HPr component phosphorylation site; TIGRFAM: dihydroxyacetone kinase, phosphotr [...]
 
 0.997
Arch_0267
Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076:IPR007419:IPR017752:IPR000447; KEGG: pac:PPA2250 anaerobic glycerol-3-phosphate dehydrogenase subunit A; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: D0YR89 Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit.
  
 
 0.826
Arch_0266
Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; COGs: COG3075 Anaerobic glycerol-3-phosphate dehydrogenase; InterPro IPR003953:IPR009158; KEGG: pac:PPA2249 anaerobic glycerol-3-phosphate dehydrogenase subunit B; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: D0YR90 Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; PFAM: FAD binding domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit.
  
 
  0.806
Arch_0555
COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: krh:KRH_11260 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: C0W772 Nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family.
  
    0.806
Arch_0265
Glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; COGs: COG0247 Fe-S oxidoreductase; InterProIPR001450:IPR004017:IPR012285:IPR017896:IPR 017753:IPR009051:IPR017900; KEGG: pac:PPA2248 sn-glycerol-3-phosphate dehydrogenase subunit C; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C2BV29 sn-glycerol-3-phosphate dehydrogenase subunit C; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; PFAM: Cysteine-rich domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit.
     
  0.800
Arch_0554
FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR004101:IPR018109:IPR001645; KEGG: bcv:Bcav_2567 FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: D0WR93 Tetrahydrofolate synthase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase.
       0.800
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
       0.800
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
       0.792
Arch_0558
KEGG: SORBIDRAFT_08g000780; hypothetical protein; SPTR: D0WR82 Putative uncharacterized protein.
       0.587
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.494
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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