STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0558KEGG: SORBIDRAFT_08g000780; hypothetical protein; SPTR: D0WR82 Putative uncharacterized protein. (112 aa)    
Predicted Functional Partners:
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.636
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
       0.597
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
       0.587
Arch_0554
FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR004101:IPR018109:IPR001645; KEGG: bcv:Bcav_2567 FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: D0WR93 Tetrahydrofolate synthase; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase.
       0.587
Arch_0555
COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: krh:KRH_11260 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: C0W772 Nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family.
       0.587
Arch_0556
Dihydroxyacetone kinase, L subunit; COGs: COG2376 Dihydroxyacetone kinase; InterPro IPR004007:IPR012737; KEGG: car:cauri_1454 dihydroxyacetone kinase; PFAM: Dak phosphatase; SPTR: A7BCU2 Putative uncharacterized protein; TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: DAK2 domain; TIGRFAM: dihydroxyacetone kinase, phosphoprotein-dependent, L subunit.
       0.587
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.503
Arch_0561
Amidohydrolase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680; KEGG: jde:Jden_0984 amidohydrolase; PFAM: amidohydrolase; SPTR: Q8VVP7 Putative uncharacterized protein; manually curated.
       0.476
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.