STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0576Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: bcv:Bcav_2532 protein of unknown function UPF0102; PFAM: protein of unknown function UPF0102; SPTR: C1RMF8 Predicted endonuclease related to Holliday junction resolvase; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family. (123 aa)    
Predicted Functional Partners:
Arch_0577
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterProIPR001208:IPR000523:IPR004482:IPR003593:IPR 020568; KEGG: kra:Krad_1408 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: D0WR55 Mg chelatase-like protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein.
 
  
 0.945
Arch_0578
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: bcv:Bcav_2511 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: D0WR54 DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
    0.903
xerC
Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
       0.822
Arch_0573
Signal peptidase I; InterProIPR011056:IPR019758:IPR000223:IPR019759:IPR 015927; KEGG: bcv:Bcav_2535 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: D0WR60 Peptidase S26A, signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S26; Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
  
    0.622
Arch_0575
Protein of unknown function DUF2469; InterPro IPR019592; KEGG: jde:Jden_0992 hypothetical protein; PFAM: Protein of unknown function DUF2469; SPTR: D0WR58 Putative CTP synthase; PFAM: Protein of unknown function (DUF2469).
       0.613
Arch_0574
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.601
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.526
Arch_0580
Peptidase S8 and S53 subtilisin kexin sedolisin; COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209:IPR014877; KEGG: pac:PPA0598 serine protease; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; Exportin 1-like; SPTR: Q6AA63 Serine protease, subtilase family; PFAM: Subtilase family; Belongs to the peptidase S8 family.
       0.419
Arch_0996
COGs: COG0658 membrane metal-binding protein; InterPro IPR004477; KEGG: jde:Jden_1561 ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; SPTR: C0W2X3 Possible ComEC operon protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein.
  
    0.408
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
     0.407
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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