STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0578DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: bcv:Bcav_2511 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: D0WR54 DNA protecting protein DprA; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA. (384 aa)    
Predicted Functional Partners:
Arch_0577
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterProIPR001208:IPR000523:IPR004482:IPR003593:IPR 020568; KEGG: kra:Krad_1408 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: D0WR55 Mg chelatase-like protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein.
 
 0.968
Arch_0576
Protein of unknown function UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509:IPR011335; KEGG: bcv:Bcav_2532 protein of unknown function UPF0102; PFAM: protein of unknown function UPF0102; SPTR: C1RMF8 Predicted endonuclease related to Holliday junction resolvase; PFAM: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family.
 
    0.903
xerC
Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
     
 0.863
Arch_1416
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: bcv:Bcav_1243 hypothetical protein; PFAM: phosphoribosyltransferase; SPTR: D0WPH2 Competence protein F; PFAM: Phosphoribosyl transferase domain.
 
 
 0.786
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.706
Arch_0573
Signal peptidase I; InterProIPR011056:IPR019758:IPR000223:IPR019759:IPR 015927; KEGG: bcv:Bcav_2535 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; SPTR: D0WR60 Peptidase S26A, signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S26; Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
 
     0.668
Arch_0574
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
 
    0.663
rimM
16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
 
   
 0.652
Arch_0996
COGs: COG0658 membrane metal-binding protein; InterPro IPR004477; KEGG: jde:Jden_1561 ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; SPTR: C0W2X3 Possible ComEC operon protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein.
 
  
 0.648
Arch_0575
Protein of unknown function DUF2469; InterPro IPR019592; KEGG: jde:Jden_0992 hypothetical protein; PFAM: Protein of unknown function DUF2469; SPTR: D0WR58 Putative CTP synthase; PFAM: Protein of unknown function (DUF2469).
       0.613
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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