STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0660UvrD/REP helicase; COGs: COG3973 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR000212; KEGG: bcv:Bcav_2428 ATP-dependent DNA helicase; PFAM: UvrD/REP helicase; SPTR: D0WQX3 Putative DNA or RNA helicase, Superfamily I; PFAM: UvrD/REP helicase. (751 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.994
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.992
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
   0.893
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
   0.893
Arch_0661
Protein of unknown function DUF75; InterPro IPR002766; KEGG: tfu:Tfu_0926 hypothetical protein; PFAM: protein of unknown function DUF75; SPTR: D0WQX2 Putative uncharacterized protein; PFAM: PAC2 family.
 
     0.626
Arch_0659
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR018062:IPR020845:IPR000873; KEGG: saq:Sare_2221 acyl-CoA synthetase; PFAM: AMP-dependent synthetase and ligase; SPTR: D0WQX6 CoA ligase; PFAM: AMP-binding enzyme.
       0.586
Arch_0904
InterPro IPR004989:IPR004347; KEGG: bcv:Bcav_2240 protein of unknown function DUF245 domain protein; PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; SPTR: D0WMP2 Proteasome accessory factor PafA2; PFAM: Pup-ligase protein.
  
     0.469
Arch_1632
KEGG: bcv:Bcav_0815 hypothetical protein; SPTR: D0WJU8 Putative uncharacterized protein.
  
     0.448
Arch_0870
InterPro IPR009061:IPR000551; KEGG: bcv:Bcav_2101 transcriptional regulator, MerR family; SMART: regulatory protein MerR; SPTR: D0WMW0 Regulatory protein, MerR family.
  
     0.425
Arch_0902
InterPro IPR004989:IPR004347; KEGG: xce:Xcel_1490 protein of unknown function DUF245 domain protein; PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; SPTR: D0WMP4 Proteasome accessory factor PafA; PFAM: Pup-ligase protein.
  
     0.419
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.