STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0678Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR011324:IPR003730; KEGG: tfu:Tfu_1114 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: Q47QW5 Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726. (256 aa)    
Predicted Functional Partners:
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
  
 0.823
Arch_0433
Alanine racemase domain protein; COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eba:ebA1768 hypothetical protein; PFAM: alanine racemase domain protein; SPTR: D0WRH4 Pyridoxal phosphate enzyme, YggS family; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family.
  
  
 0.815
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.758
Arch_0680
Protein of unknown function YGGT; InterPro IPR003425; KEGG: fra:Francci3_1422 hypothetical protein; PFAM: protein of unknown function YGGT; SPTR: C2BWZ3 Transmembrane protein; PFAM: YGGT family.
  
  
 0.708
Arch_0673
Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR018488:IPR001182; KEGG: kra:Krad_3200 cell division protein FtsW; PFAM: cell cycle protein; SPTR: D0WQN1 Cell division protein FtsW; PFAM: Cell cycle protein; Belongs to the SEDS family.
 
  
 0.707
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
  
 0.679
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
     
 0.655
Arch_0668
Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR012338:IPR005311:IPR001460; KEGG: bcv:Bcav_2416 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: D0WQW3 Penicillin binding protein transpeptidase domain protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain.
 
   
 0.631
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
     0.580
Arch_0667
KEGG: krh:KRH_14890 hypothetical protein; SPTR: D0WQW4 Putative membrane protein.
 
     0.553
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.