STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0678Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR011324:IPR003730; KEGG: tfu:Tfu_1114 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: Q47QW5 Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726. (256 aa)    
Predicted Functional Partners:
Arch_1408
COGs: COG1816 Adenosine deaminase; InterPro IPR001365:IPR006330:IPR013838:IPR006650; KEGG: bcv:Bcav_3173 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: Adenosine deaminase; SPTR: D0WPG6 Adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase.
 
  
  0.914
apt
Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
  0.908
Arch_0113
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
 0.903
Arch_1262
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.903
Arch_0025
5'-Nucleotidase domain protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR008334:IPR006179; KEGG: mxa:MXAN_5361 putative 5'-nucleotidase; PFAM: 5'-Nucleotidase domain protein; SPTR: A8TK86 5'-Nucleotidase; PFAM: 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
     
  0.900
Arch_0203
LPXTG-motif cell wall anchor domain protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334:IPR019931:IPR006179; KEGG: cjk:jk1044 putative 5'-nucleotidase family protein; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; SPTR: Q4JVE9 Putative 5'-nucleotidase family protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; TIGRFAM: LPXTG-motif cell wall anchor domain; Belongs to the 5'-nucleotidase family.
     
  0.900
Arch_0239
LPXTG-motif cell wall anchor domain protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334:IPR019931:IPR006179; KEGG: cgt:cgR_0412 hypothetical protein; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; SPTR: D0WQ91 5-nucleotidase; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: 5'-nucleotidase, C-terminal domain; TIGRFAM: LPXTG-motif cell wall anchor domain.
     
  0.900
Arch_1005
COGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR000845; KEGG: kse:Ksed_10970 purine-nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; SPTR: C0W1W4 Purine nucleoside phosphorylase; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD).
     
  0.900
Arch_1216
HAD-superfamily hydrolase, subfamily IIA; COGs: COG0647 sugar phosphatase of the HAD superfamily; InterPro IPR006357:IPR005834; KEGG: jde:Jden_2424 HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: D0WLK8 Sugar phosphatase/hydrolase of the HAD family protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; TIGRFAM: HAD-superfamily subfamily IIA hydrolase, TIGR01457; Haloacid Dehalogenase Superfamily Class (subfamily) IIA.
     
  0.900
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
  
 0.807
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.