STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0688Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: bcv:Bcav_1772 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: C5C4Q0 Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family; Belongs to the Fur family. (132 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.860
Arch_0687
COGs: COG0586 membrane-associated protein; KEGG: nml:Namu_0645 SNARE associated Golgi protein; SPTR: C0W0A7 Putative uncharacterized protein; PFAM: SNARE associated Golgi protein.
       0.838
Arch_0690
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: jde:Jden_1534 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: D1BF11 ATPase component of Mn/Zn ABC-type transporter; PFAM: ABC transporter.
  
  
 0.805
Arch_0686
RNA-binding S4 domain protein; COGs: COG2501 conserved hypothetical protein; InterPro IPR002942; KEGG: xce:Xcel_1301 RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; SPTR: D0WQU2 RNA-binding S4; PFAM: S4 domain.
  
    0.798
Arch_0691
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: gym:GYMC10_3445 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: C0W0B1 Metal ABC superfamily ATP binding cassette transporter, binding protein; PFAM: Periplasmic solute binding protein family.
  
  
 0.793
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
 
 0.784
Arch_0689
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: bcv:Bcav_1773 ABC-3 protein; PFAM: ABC-3 protein; SPTR: C0W322 Metal cation ABC superfamily ATP binding cassette transporter, membrane protein; PFAM: ABC 3 transport family.
  
  
 0.743
Arch_1323
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.743
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.726
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.680
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.