| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Arch_0067 | Arch_0723 | Arch_0067 | Arch_0723 | dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR016040:IPR005888; KEGG: xce:Xcel_2563 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: D0WPK4 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | 0.423 |
| Arch_0254 | Arch_0723 | Arch_0254 | Arch_0723 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | 0.440 |
| Arch_0254 | dnaG | Arch_0254 | Arch_0701 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.545 |
| Arch_0696 | Arch_0723 | Arch_0696 | Arch_0723 | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006261:IPR006674; KEGG: bcv:Bcav_1786 deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: D0WQT2 Putative deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; uncharacterized domain HDIG; Belongs to the dGTPase family. Type 2 subfamily. | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | 0.408 |
| Arch_0696 | dnaG | Arch_0696 | Arch_0701 | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006261:IPR006674; KEGG: bcv:Bcav_1786 deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: D0WQT2 Putative deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; uncharacterized domain HDIG; Belongs to the dGTPase family. Type 2 subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.659 |
| Arch_0722 | Arch_0723 | Arch_0722 | Arch_0723 | Glycoside hydrolase, family 20, catalytic core; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterProIPR001540:IPR017853:IPR008979:IPR000421:IPR 013781:IPR015883; KEGG: sgr:SGR_2685 putative beta-N-acetylglucosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; coagulation factor 5/8 type domain protein; SPTR: A8REL0 Putative uncharacterized protein; PFAM: F5/8 type C domain; Glycosyl hydrolase family 20, catalytic domain; TIGRFAM: LPXTG-motif cell wall anchor domain. | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | 0.519 |
| Arch_0722 | Arch_0724 | Arch_0722 | Arch_0724 | Glycoside hydrolase, family 20, catalytic core; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterProIPR001540:IPR017853:IPR008979:IPR000421:IPR 013781:IPR015883; KEGG: sgr:SGR_2685 putative beta-N-acetylglucosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; coagulation factor 5/8 type domain protein; SPTR: A8REL0 Putative uncharacterized protein; PFAM: F5/8 type C domain; Glycosyl hydrolase family 20, catalytic domain; TIGRFAM: LPXTG-motif cell wall anchor domain. | KEGG: bcv:Bcav_1829 hypothetical protein; SPTR: D0WQQ0 Putative uncharacterized protein. | 0.494 |
| Arch_0723 | Arch_0067 | Arch_0723 | Arch_0067 | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR016040:IPR005888; KEGG: xce:Xcel_2563 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: D0WPK4 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. | 0.423 |
| Arch_0723 | Arch_0254 | Arch_0723 | Arch_0254 | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.440 |
| Arch_0723 | Arch_0696 | Arch_0723 | Arch_0696 | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006261:IPR006674; KEGG: bcv:Bcav_1786 deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: D0WQT2 Putative deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative; uncharacterized domain HDIG; Belongs to the dGTPase family. Type 2 subfamily. | 0.408 |
| Arch_0723 | Arch_0722 | Arch_0723 | Arch_0722 | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | Glycoside hydrolase, family 20, catalytic core; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterProIPR001540:IPR017853:IPR008979:IPR000421:IPR 013781:IPR015883; KEGG: sgr:SGR_2685 putative beta-N-acetylglucosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; coagulation factor 5/8 type domain protein; SPTR: A8REL0 Putative uncharacterized protein; PFAM: F5/8 type C domain; Glycosyl hydrolase family 20, catalytic domain; TIGRFAM: LPXTG-motif cell wall anchor domain. | 0.519 |
| Arch_0723 | Arch_0724 | Arch_0723 | Arch_0724 | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | KEGG: bcv:Bcav_1829 hypothetical protein; SPTR: D0WQQ0 Putative uncharacterized protein. | 0.855 |
| Arch_0723 | Arch_1457 | Arch_0723 | Arch_1457 | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.418 |
| Arch_0723 | Arch_1812 | Arch_0723 | Arch_1812 | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | Putative transcriptional regulator, GntR family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR015424:IPR004839:IPR015421; KEGG: bcv:Bcav_4214 putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; SPTR: D0WL32 Aminotransferase classes I and II protein; PFAM: Aminotransferase class I and II. | 0.461 |
| Arch_0723 | dnaG | Arch_0723 | Arch_0701 | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.404 |
| Arch_0723 | polA | Arch_0723 | Arch_0896 | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.497 |
| Arch_0724 | Arch_0722 | Arch_0724 | Arch_0722 | KEGG: bcv:Bcav_1829 hypothetical protein; SPTR: D0WQQ0 Putative uncharacterized protein. | Glycoside hydrolase, family 20, catalytic core; COGs: COG3525 N-acetyl-beta-hexosaminidase; InterProIPR001540:IPR017853:IPR008979:IPR000421:IPR 013781:IPR015883; KEGG: sgr:SGR_2685 putative beta-N-acetylglucosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; coagulation factor 5/8 type domain protein; SPTR: A8REL0 Putative uncharacterized protein; PFAM: F5/8 type C domain; Glycosyl hydrolase family 20, catalytic domain; TIGRFAM: LPXTG-motif cell wall anchor domain. | 0.494 |
| Arch_0724 | Arch_0723 | Arch_0724 | Arch_0723 | KEGG: bcv:Bcav_1829 hypothetical protein; SPTR: D0WQQ0 Putative uncharacterized protein. | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | 0.855 |
| Arch_1457 | Arch_0723 | Arch_1457 | Arch_0723 | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | 0.418 |
| Arch_1812 | Arch_0723 | Arch_1812 | Arch_0723 | Putative transcriptional regulator, GntR family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR015424:IPR004839:IPR015421; KEGG: bcv:Bcav_4214 putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; SPTR: D0WL32 Aminotransferase classes I and II protein; PFAM: Aminotransferase class I and II. | Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: svi:Svir_06980 conserved hypothetical protein TIGR00486; PFAM: protein of unknown function DUF34; SPTR: C7MVQ0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486. | 0.461 |