STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0737KEGG: stp:Strop_2530 hypothetical protein; SPTR: D0WQM7 Putative oxidoreductase. (100 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.824
Arch_0735
COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR011053:IPR004167:IPR003016:IPR000089:IPR 014276:IPR001078; KEGG: rmu:RMDY18_07280 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: A7BC68 Putative uncharacterized protein; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: [...]
   
   0.643
Arch_0736
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR000815:IPR016156:IPR012999:IPR 004099:IPR006258; KEGG: jde:Jden_1475 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: D0WQM8 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
   
   0.631
Arch_0750
COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterProIPR012337:IPR000305:IPR006055:IPR006054:IPR 013520; KEGG: bcv:Bcav_1900 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; SPTR: D0WQL3 Putative DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
  
     0.608
Arch_0990
Membrane-flanked domain protein; InterPro IPR005182; KEGG: nfa:nfa9960 hypothetical protein; PFAM: membrane-flanked domain; SPTR: D0WN69 Bacterial membrane flanked domain protein; manually curated; PFAM: Bacterial membrane flanked domain.
  
     0.604
Arch_1805
InterPro IPR016196:IPR011701; KEGG: bcv:Bcav_4203 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: C1RM73 Major Facilitator Superfamily transporter; PFAM: Major Facilitator Superfamily.
  
     0.584
Arch_1435
VanW family protein; COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391; KEGG: jde:Jden_0796 VanW family protein; PFAM: VanW family protein; SPTR: D0WPN1 VanW like protein; PFAM: Putative peptidoglycan binding domain; VanW like protein.
  
     0.582
Arch_0555
COGs: COG0105 Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: krh:KRH_11260 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: C0W772 Nucleoside-diphosphate kinase; PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family.
    
 
 0.557
Arch_1364
Alpha/beta hydrolase fold-3 domain protein; COGs: COG0657 Esterase/lipase; InterPro IPR013094:IPR002168; KEGG: ele:Elen_1835 alpha/beta hydrolase fold-3 domain protein; PFAM: Alpha/beta hydrolase fold-3 domain protein; SPTR: D0WP07 Acetyl esterase; PFAM: alpha/beta hydrolase fold.
  
  0.435
Arch_0608
GCN5-related N-acetyltransferase; COGs: COG3393 acetyltransferase; InterPro IPR016181:IPR000182; KEGG: bcv:Bcav_2497 GCN5-related protein N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: D0WR27 Acetyltransferase, GNAT family protein; PFAM: Acetyltransferase (GNAT) family.
  
     0.431
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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