STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_07983'-5' exonuclease; COGs: COG0349 Ribonuclease D; InterPro IPR012337:IPR002562:IPR002121; KEGG: bcv:Bcav_1962 3'-5' exonuclease; PFAM: 3'-5' exonuclease; HRDC domain protein; SMART: 3'-5' exonuclease; HRDC domain protein; SPTR: D0WQH3 Putative ribonuclease D; PFAM: 3'-5' exonuclease; HRDC domain; TIGRFAM: ribonuclease D. (398 aa)    
Predicted Functional Partners:
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
   
 0.998
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.992
Arch_0894
RNA binding S1 domain protein; COGs: COG0539 Ribosomal protein S1; InterPro IPR000110:IPR016027:IPR003029:IPR012340; KEGG: jde:Jden_1229 RNA binding S1 domain protein; PFAM: RNA binding S1 domain protein; SPTR: D0WMQ6 Ribosomal protein S1; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
  
 0.991
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
  0.989
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
  0.967
Arch_0127
COGs: COG1643 HrpA-like helicase; InterProIPR014001:IPR003593:IPR001650:IPR007502:IPR 011709:IPR014021:IPR010222; KEGG: jde:Jden_0240 ATP-dependent helicase HrpA; PFAM: helicase-associated domain protein; helicase domain protein; protein of unknown function DUF1605; SMART: DEAD-like helicase; AAA ATPase; helicase domain protein; SPTR: D0WKL4 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); Domain of unknown function (DUF3418); Domain of unknown function (DUF1605); TIGRFAM: ATP-dependent heli [...]
  
 0.949
Arch_1783
ATP-dependent helicase HrpB; COGs: COG1643 HrpA-like helicase; InterProIPR002464:IPR014001:IPR001650:IPR014021:IPR 011545:IPR007502:IPR013689:IPR010225; KEGG: tcu:Tcur_1990 ATP-dependent helicase HrpB; PFAM: Helicase ATP-dependent domain protein; helicase domain protein; DEAD/DEAH box helicase domain protein; helicase-associated domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D1BHA4 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: Helicase conserved C-terminal domain; ATP-dependent helicase C-terminal; Helicase associated domain (HA2); [...]
  
 0.942
Arch_0799
KEGG: bcv:Bcav_1965 hypothetical protein; SPTR: D0WQH2 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3000).
 
    0.939
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
    
   0.857
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.857
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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