STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0818COGs: COG2339 membrane protein; KEGG: bcv:Bcav_1985 membrane protein; SPTR: C5C5P9 Membrane protein. (383 aa)    
Predicted Functional Partners:
thrS
COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR018158:IPR018163:IPR004154:IPR006195:IPR 002320:IPR012947:IPR002314; KEGG: bfa:Bfae_13900 threonyl-tRNA synthetase/Ser-tRNA(Thr) hydrolase; PFAM: tRNA synthetase class II (G H P and S); Threonyl/alanyl tRNA synthetase SAD; Anticodon-binding domain protein; SPTR: D0YSQ6 Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II [...]
       0.801
Arch_0814
CDP-alcohol phosphatidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR017871:IPR000462; KEGG: xce:Xcel_1658 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: D0WQG4 Putative CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.800
Arch_0815
COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: xce:Xcel_1659 lipid A biosynthesis acyltransferase; PFAM: lipid A biosynthesis acyltransferase; SPTR: D0WQG3 Lipid A biosynthesis lauroyl acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase.
       0.800
Arch_0816
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: xce:Xcel_1660 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: D0WQG2 Phosphatidylinositol alpha-mannosyltransferase; PFAM: Glycosyl transferases group 1.
       0.800
Arch_0817
KEGG: xce:Xcel_1661 hypothetical protein; SPTR: D0WQG1 Putative uncharacterized protein.
       0.800
Arch_0819
NUDIX hydrolase; InterPro IPR020476:IPR015797:IPR020084:IPR000086; KEGG: bcv:Bcav_1987 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0WQF9 MutT/NUDIX family protein; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
       0.795
Arch_0820
Protein of unknown function DUF28; COGs: COG0217 conserved hypothetical protein; InterPro IPR002876:IPR017856; KEGG: ami:Amir_2110 protein of unknown function DUF28; PFAM: protein of unknown function DUF28; SPTR: D0WQF1 Protein YebC; PFAM: Domain of unknown function DUF28; TIGRFAM: conserved hypothetical protein TIGR01033.
       0.610
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.608
Arch_0812
COGs: COG1760 L-serine deaminase; InterPro IPR004644:IPR005131:IPR005130; KEGG: aau:AAur_3830 L-serine ammonia-lyase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; PRIAM: L-serine ammonia-lyase; SPTR: A1RB97 L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form.
       0.517
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.511
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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