STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0831COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: kse:Ksed_15250 Zn-dependent hydrolase, glyoxylase; SPTR: D0WQE0 Metallo-beta-lactamase family protein; PFAM: Metallo-beta-lactamase superfamily. (241 aa)    
Predicted Functional Partners:
Arch_1670
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001763:IPR016156:IPR013027:IPR004099; KEGG: cdi:DIP1748 putative oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: C2CQM4 CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain.
  
 0.958
Arch_1358
Beta-lactamase domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: pmx:PERMA_1508 beta-lactamase domain protein; SPTR: D0WP02 Metallo-beta-lactamase family protein; PFAM: Metallo-beta-lactamase superfamily.
  
  
 
0.927
Arch_0832
COGs: COG0124 Histidyl-tRNA synthetase; InterProIPR004154:IPR004516:IPR006195:IPR015807:IPR 002314; KEGG: xce:Xcel_1680 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: D0WQD9 Histidine--tRNA ligase; TIGRFAM: histidyl-tRNA synthetase; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.
  
    0.736
Arch_0833
KEGG: kse:Ksed_08870 hypothetical protein; SPTR: D0WQD8 Putative ATP/GTP-binding protein; PFAM: Dynamin family.
       0.711
Arch_0830
InterPro IPR007139; KEGG: bcv:Bcav_2001 protein of unknown function DUF349; PFAM: protein of unknown function DUF349; SPTR: C5C5R5 Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF349).
  
    0.644
Arch_0834
GTP-binding protein HSR1-related protein; InterPro IPR002917; KEGG: kse:Ksed_08880 predicted GTPase; PFAM: GTP-binding protein HSR1-related; SPTR: C0W3Q0 ATP/GTP-binding protein; PFAM: GTPase of unknown function.
       0.580
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
 
 0.478
Arch_1749
Transcriptional regulator, LuxR family; InterPro IPR000792:IPR016032:IPR011991; KEGG: sco:SCO1353 transcriptional regulator; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Q7WWP4 Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, luxR family.
    
 
 0.477
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.467
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
   
 
 0.456
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (32%) [HD]