STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
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[Homology]
Score
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (511 aa)    
Predicted Functional Partners:
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
  
 0.710
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
     
 0.655
Arch_0866
DEAD/DEAH box helicase domain protein; COGs: COG4581 Superfamily II RNA helicase; InterProIPR014001:IPR001650:IPR014021:IPR011545:IPR 012961; KEGG: ace:Acel_1206 DSH domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DSH domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D0WMW7 ATP-dependent RNA helicase, DEAD/DEAH box family; PFAM: Helicase conserved C-terminal domain; DSHCT (NUC185) domain; DEAD/DEAH box helicase.
       0.632
Arch_0865
Hypothetical protein; KEGG: tcu:Tcur_2317 transcriptional regulator-like protein; SPTR: D0WMW9 Putative uncharacterized protein.
 
     0.557
Arch_0750
COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterProIPR012337:IPR000305:IPR006055:IPR006054:IPR 013520; KEGG: bcv:Bcav_1900 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; SPTR: D0WQL3 Putative DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
 
   
 0.516
Arch_0864
COGs: COG2378 transcriptional regulator protein; KEGG: kse:Ksed_13990 predicted transcriptional regulator; SPTR: D0WMX0 Putative uncharacterized protein.
       0.495
Arch_0857
Primosome assembly protein PriA; COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; KEGG: tfu:Tfu_1073 primosome assembly protein PriA; SPTR: D0WMZ0 Primosomal protein; TIGRFAM: primosomal protein N'; glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type.
 
   
 0.457
tatA
Sec-independent translocation protein mttA/Hcf106; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
     
 0.451
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
     
 0.449
Arch_0820
Protein of unknown function DUF28; COGs: COG0217 conserved hypothetical protein; InterPro IPR002876:IPR017856; KEGG: ami:Amir_2110 protein of unknown function DUF28; PFAM: protein of unknown function DUF28; SPTR: D0WQF1 Protein YebC; PFAM: Domain of unknown function DUF28; TIGRFAM: conserved hypothetical protein TIGR01033.
 
     0.428
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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