STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0870InterPro IPR009061:IPR000551; KEGG: bcv:Bcav_2101 transcriptional regulator, MerR family; SMART: regulatory protein MerR; SPTR: D0WMW0 Regulatory protein, MerR family. (250 aa)    
Predicted Functional Partners:
Arch_0871
COGs: COG1716 FOG: FHA domain; InterPro IPR008984:IPR000253; KEGG: bcv:Bcav_2102 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: D0WMV9 GarA protein; PFAM: FHA domain.
 
    0.889
Arch_1114
Domain of unknown function DUF2017; InterPro IPR018561; KEGG: bcv:Bcav_2740 hypothetical protein; PFAM: Domain of unknown function DUF2017; SPTR: D0WNI6 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF2017).
  
    0.793
Arch_0869
InterPro IPR009061:IPR000551; KEGG: bcv:Bcav_2099 transcriptional regulator, MerR family; SMART: regulatory protein MerR; SPTR: C5C6E6 Transcriptional regulator, MerR family.
 
   
 0.761
Arch_0872
COGs: COG0308 Aminopeptidase N; InterPro IPR014782:IPR016059:IPR012778; KEGG: kse:Ksed_24070 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: C7NFC1 Aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Peptidase family M1; Domain of unknown function (DUF3358); TIGRFAM: aminopeptidase N, Streptomyces lividans type.
  
    0.623
Arch_0170
Heat shock protein DnaJ domain protein; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623:IPR002939:IPR008971:IPR003095; KEGG: bcv:Bcav_3707 chaperone DnaJ domain protein; PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: D0WLG5 DnaJ protein; PFAM: DnaJ domain; DnaJ C terminal region.
  
 
 0.608
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.608
Arch_0661
Protein of unknown function DUF75; InterPro IPR002766; KEGG: tfu:Tfu_0926 hypothetical protein; PFAM: protein of unknown function DUF75; SPTR: D0WQX2 Putative uncharacterized protein; PFAM: PAC2 family.
  
     0.602
Arch_1623
Chromogranin/secretogranin; InterPro IPR001990; KEGG: xce:Xcel_2933 hypothetical protein; PFAM: Chromogranin/secretogranin; SPTR: D0WJT5 Putative secreted protein.
  
     0.550
Arch_1068
InterPro IPR011251; KEGG: bcv:Bcav_1628 hypothetical protein; SPTR: D0WNB4 Nitrilotriacetate monooxygenase.
  
     0.534
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.527
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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