STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkCOGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015911:IPR015824:IPR015901; KEGG: jde:Jden_1257 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: D0WMT2 Phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
Arch_0884
COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020832:IPR016040:IPR020830:IPR020831:IPR 006424:IPR020828:IPR020829; KEGG: cdi:DIP1310 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: Q6NH35 Glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, [...]
 0.999
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.995
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.989
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: pac:PPA2131 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: D0WNS5 Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 
 0.971
Arch_0192
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.947
Arch_0899
COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015813:IPR015795:IPR011037:IPR 018209:IPR015794:IPR001697; KEGG: bcv:Bcav_2215 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: D0WMQ1 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.938
Arch_0881
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
     
 0.798
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
  
  
 0.794
Arch_0880
Transketolase; COGs: COG0021 Transketolase; InterProIPR009014:IPR005474:IPR015941:IPR005478:IPR 005475:IPR005476; KEGG: jde:Jden_1264 transketolase; PFAM: Transketolase domain protein; Transketolase central region; SPTR: D0WMT7 Transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
  
 
 0.772
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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