STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
Arch_0898Response regulator receiver and ANTAR domain protein; COGs: COG3707 Response regulator with putative antiterminator output domain; InterProIPR011006:IPR001789:IPR008327:IPR005561:IPR 011991; KEGG: bfa:Bfae_14950 response regulator with putative antiterminator output domain; PFAM: response regulator receiver; ANTAR domain protein; SMART: response regulator receiver; SPTR: D0WMQ2 Two-component system response regulator; PFAM: Response regulator receiver domain; ANTAR domain. (209 aa)    
Predicted Functional Partners:
Arch_0411
COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR013656:IPR011495; KEGG: bcv:Bcav_2829 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: D0WS29 Sensor histidine kinase; PFAM: Histidine kinase; Signal transduction histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box.
 
   
 0.860
Arch_1664
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR011006:IPR016032:IPR001867; KEGG: mlu:Mlut_03750 PhoP-like protein; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C0W5A5 Response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
   
 0.643
Arch_1130
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR000463:IPR001867; KEGG: xce:Xcel_2992 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: D0YTJ0 Transcriptional regulatory protein ResD; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
   
 0.632
Arch_0899
COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015813:IPR015795:IPR011037:IPR 018209:IPR015794:IPR001697; KEGG: bcv:Bcav_2215 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: D0WMQ1 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
       0.589
Arch_0894
RNA binding S1 domain protein; COGs: COG0539 Ribosomal protein S1; InterPro IPR000110:IPR016027:IPR003029:IPR012340; KEGG: jde:Jden_1229 RNA binding S1 domain protein; PFAM: RNA binding S1 domain protein; SPTR: D0WMQ6 Ribosomal protein S1; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1.
  
    0.586
Arch_1245
NifC-like ABC-type porter; COGs: COG4149 ABC-type molybdate transport system permease component; InterProIPR006469:IPR011867:IPR003439:IPR000515:IPR 003593; KEGG: sgr:SGR_3501 putative ABC transporter ATPase and permease component; PFAM: ABC transporter related; binding-protein-dependent transport systems inner membrane component; SMART: AAA ATPase; SPTR: A7BBD7 Putative uncharacterized protein; TIGRFAM: NifC-like ABC-type porter; molybdate ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter; TIGRFAM: molyb [...]
  
  
 0.583
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
       0.491
Arch_1131
Histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003594:IPR009082:IPR005467:IPR003661:IPR 004358; KEGG: xce:Xcel_2991 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: D1BZA0 Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
     0.480
Arch_0642
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003594:IPR009082:IPR003661:IPR 005467; KEGG: xce:Xcel_2991 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: C2KNB8 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
  
 0.477
Arch_0719
KEGG: bcv:Bcav_1811 hypothetical protein; SPTR: C0W3W7 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3052).
   
    0.458
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.