STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arcAAA ATPase central domain protein; COGs: COG1222 ATP-dependent 26S proteasome regulatory subunit; InterPro IPR003960:IPR003593:IPR003959; KEGG: xce:Xcel_1485 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: C1RM61 ATP-dependent 26S proteasome regulatory subunit; PFAM: ATPase family associated with various cellular activities (AAA). (506 aa)    
Predicted Functional Partners:
Arch_0903
Protein of unknown function DUF797; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Belongs to the prokaryotic ubiquitin-like protein family.
   
 
 0.998
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.997
Arch_0289
Peptidase S1 and S6 chymotrypsin/Hap; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001254:IPR009003:IPR001940; KEGG: bcv:Bcav_3234 2-alkenal reductase; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: C5C0T2 2-alkenal reductase; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF).
   
 0.988
Arch_0902
InterPro IPR004989:IPR004347; KEGG: xce:Xcel_1490 protein of unknown function DUF245 domain protein; PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; SPTR: D0WMP4 Proteasome accessory factor PafA; PFAM: Pup-ligase protein.
 
  
 0.987
Arch_0904
InterPro IPR004989:IPR004347; KEGG: bcv:Bcav_2240 protein of unknown function DUF245 domain protein; PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; SPTR: D0WMP2 Proteasome accessory factor PafA2; PFAM: Pup-ligase protein.
 
  
 0.964
Arch_0906
COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816; KEGG: bcv:Bcav_2243 tRNA methyltransferase complex GCD14 subunit; PFAM: tRNA methyltransferase complex GCD14 subunit; PRIAM: tRNA (adenine-N(1)-)-methyltransferase; SPTR: D0WMP0 SAM-dependent methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit.
 
     0.880
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  0.865
Arch_0139
KEGG: bcv:Bcav_2625 hypothetical protein; SPTR: D0WKD8 Putative uncharacterized protein.
    
  0.803
Arch_0901
InterPro IPR001179; KEGG: bcv:Bcav_2236 peptidylprolyl isomerase FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: D0WMP5 Putative peptidyl-prolyl cis-trans isomerase, FKBP-type; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
  
   0.774
Arch_0319
SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR001412:IPR003395; KEGG: cms:CMS_2145 putative nuclease; PFAM: SMC domain protein; SPTR: D0WRP2 Putative nuclease sbcCD subunit C; TIGRFAM: DNA sulfur modification protein DndD; exonuclease SbcC.
   
 
 0.707
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.