STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0906COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816; KEGG: bcv:Bcav_2243 tRNA methyltransferase complex GCD14 subunit; PFAM: tRNA methyltransferase complex GCD14 subunit; PRIAM: tRNA (adenine-N(1)-)-methyltransferase; SPTR: D0WMP0 SAM-dependent methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit. (365 aa)    
Predicted Functional Partners:
arc
AAA ATPase central domain protein; COGs: COG1222 ATP-dependent 26S proteasome regulatory subunit; InterPro IPR003960:IPR003593:IPR003959; KEGG: xce:Xcel_1485 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: C1RM61 ATP-dependent 26S proteasome regulatory subunit; PFAM: ATPase family associated with various cellular activities (AAA).
 
     0.890
Arch_0908
HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR006402:IPR005834; KEGG: kse:Ksed_13910 haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having dd or ED; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: C7NHR1 Haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 wi [...]
     0.888
Arch_0904
InterPro IPR004989:IPR004347; KEGG: bcv:Bcav_2240 protein of unknown function DUF245 domain protein; PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; SPTR: D0WMP2 Proteasome accessory factor PafA2; PFAM: Pup-ligase protein.
 
     0.831
Arch_0902
InterPro IPR004989:IPR004347; KEGG: xce:Xcel_1490 protein of unknown function DUF245 domain protein; PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; SPTR: D0WMP4 Proteasome accessory factor PafA; PFAM: Pup-ligase protein.
 
     0.828
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
 0.819
Arch_0903
Protein of unknown function DUF797; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Belongs to the prokaryotic ubiquitin-like protein family.
       0.788
Arch_0901
InterPro IPR001179; KEGG: bcv:Bcav_2236 peptidylprolyl isomerase FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; SPTR: D0WMP5 Putative peptidyl-prolyl cis-trans isomerase, FKBP-type; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase.
  
   0.757
Arch_0907
Conserved hypothetical protein; COGs: COG2887 RecB family exonuclease; KEGG: sco:SCO1653 hypothetical protein; SPTR: D0WMN9 RecB family exonuclease; PFAM: Protein of unknown function (DUF2800).
       0.665
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
       0.644
Arch_0899
COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015813:IPR015795:IPR011037:IPR 018209:IPR015794:IPR001697; KEGG: bcv:Bcav_2215 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: D0WMQ1 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
       0.636
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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