STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0908HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR006402:IPR005834; KEGG: kse:Ksed_13910 haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having dd or ED; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: C7NHR1 Haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 wi [...] (221 aa)    
Predicted Functional Partners:
Arch_0906
COGs: COG2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferase; InterPro IPR014816; KEGG: bcv:Bcav_2243 tRNA methyltransferase complex GCD14 subunit; PFAM: tRNA methyltransferase complex GCD14 subunit; PRIAM: tRNA (adenine-N(1)-)-methyltransferase; SPTR: D0WMP0 SAM-dependent methyltransferase; PFAM: tRNA methyltransferase complex GCD14 subunit.
     0.877
uppP
Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
 
     0.834
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
  
  
 0.734
Arch_0910
COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: xce:Xcel_1477 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: D1BS15 Aldo/keto reductase; PFAM: Aldo/keto reductase family.
  
    0.655
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.530
Arch_1278
Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004305:IPR016084:IPR004399; KEGG: pac:PPA0110 thiamine-phosphate pyrophosphorylase; PFAM: Phosphomethylpyrimidine kinase type-1; TENA/THI-4 domain protein; SPTR: Q6ABQ9 Putative thiamine biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TENA/THI-4/PQQC family; TIGRFAM: phosphomethylpyrimidine kinase.
       0.493
Arch_1589
PTS system, N-acetylglucosamine-specific IIBC subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001996:IPR013013:IPR003352:IPR018113:IPR 010974:IPR011535; KEGG: car:cauri_0239 PTS system, N-acetylglucosamine-specific IIABC component; PFAM: phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: C2GFH2 Pts system, N-acetylglucosamine-specific IIABC component; TIGRFAM: PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: Phosph [...]
  
  
 0.410
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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