STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0910COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: xce:Xcel_1477 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: D1BS15 Aldo/keto reductase; PFAM: Aldo/keto reductase family. (313 aa)    
Predicted Functional Partners:
uppP
Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
  
    0.690
Arch_0908
HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR006402:IPR005834; KEGG: kse:Ksed_13910 haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having dd or ED; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: C7NHR1 Haloacid dehalogenase superfamily protein, subfamily IA, variant 3 with third motif having DD or ED; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 wi [...]
  
    0.685
Arch_0263
Major intrinsic protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425; KEGG: jde:Jden_0486 major intrinsic protein; PFAM: major intrinsic protein; SPTR: C2KN37 MIP family major intrinsic protein channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.620
Arch_1792
COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR018170:IPR001395:IPR020471; KEGG: mgi:Mflv_4697 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: A4TFA5 2,5-didehydrogluconate reductase; PFAM: Aldo/keto reductase family.
 
 
 0.607
Arch_0488
COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395:IPR018170:IPR020471; KEGG: krh:KRH_00260 2,5-diketo-D-gluconic acid reductase; PFAM: aldo/keto reductase; PRIAM: 2,5-didehydrogluconate reductase; SPTR: P06632 2,5-diketo-D-gluconic acid reductase A; PFAM: Aldo/keto reductase family.
 
 
 0.597
Arch_1554
Redox-active disulfide protein 2; InterPro IPR012335:IPR005243:IPR012336; KEGG: mva:Mvan_5315 redox-active disulfide protein 2; SPTR: C1RG08 Small redox-active disulfide protein 2; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2.
   
 
 0.470
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.469
Arch_0911
Domain of unknown function DUF1994; InterPro IPR018532; KEGG: bde:BDP_1345 conserved hypothetical secreted protein; PFAM: Domain of unknown function DUF1994; SPTR: C0W3G0 Possible secreted protein; PFAM: Uncharacterized conserved protein (DUF2081); Domain of unknown function (DUF1994).
       0.466
Arch_0737
KEGG: stp:Strop_2530 hypothetical protein; SPTR: D0WQM7 Putative oxidoreductase.
    
   0.463
Arch_0096
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.432
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.