STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0939NUDIX hydrolase; InterPro IPR015797:IPR000086; KEGG: xce:Xcel_1348 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0WMJ2 MutT/NUDIX family protein; PFAM: NUDIX domain. (205 aa)    
Predicted Functional Partners:
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.867
Arch_0835
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR000629:IPR014001:IPR001650:IPR014021:IPR 014014:IPR011545:IPR005580; KEGG: jde:Jden_1307 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; DbpA RNA-binding domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D0WN23 ATP-dependent RNA helicase DeaD; PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
  
 0.864
Arch_1234
DEAD/DEAH box helicase domain protein; COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR014021:IPR001650:IPR014014:IPR000629:IPR 014001:IPR011545; KEGG: bcv:Bcav_2906 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D0WNN3 ATP-dependent RNA helicase DeaD; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
  
 0.864
Arch_0944
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
     
 0.831
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.827
Arch_0941
KEGG: xce:Xcel_1345 hypothetical protein; SPTR: D0WMJ0 Putative uncharacterized protein.
       0.822
Arch_0942
KEGG: kra:Krad_3145 hypothetical protein; SPTR: D0WMI9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3186).
       0.822
Arch_0943
Thiamin pyrophosphokinase catalytic region; COGs: COG4825 Uncharacterized membrane-anchored protein; InterPro IPR007371; KEGG: bcv:Bcav_2354 thiamin pyrophosphokinase catalytic region; PFAM: Thiamin pyrophosphokinase catalytic region; SPTR: D0WMI8 Thiamin pyrophosphokinase, catalytic domain protein; PFAM: Thiamine pyrophosphokinase C terminal; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase.
       0.822
Arch_0940
COGs: COG0728 membrane protein putative virulence factor; InterPro IPR004268:IPR017441; KEGG: bcv:Bcav_2351 virulence factor MviN family protein; PFAM: virulence factor MVIN family protein; SPTR: D0WMJ1 Putative integral membrane protein MviN; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN.
  
    0.802
Arch_0946
COGs: COG1189 rRNA methylase; InterPro IPR002942:IPR004538:IPR002877; KEGG: kra:Krad_3149 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: A7BC42 Putative uncharacterized protein; TIGRFAM: hemolysin A; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein.
 
    0.766
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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