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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0944DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (564 aa)    
Predicted Functional Partners:
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.939
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.914
Arch_0943
Thiamin pyrophosphokinase catalytic region; COGs: COG4825 Uncharacterized membrane-anchored protein; InterPro IPR007371; KEGG: bcv:Bcav_2354 thiamin pyrophosphokinase catalytic region; PFAM: Thiamin pyrophosphokinase catalytic region; SPTR: D0WMI8 Thiamin pyrophosphokinase, catalytic domain protein; PFAM: Thiamine pyrophosphokinase C terminal; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase.
       0.866
Arch_0942
KEGG: kra:Krad_3145 hypothetical protein; SPTR: D0WMI9 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3186).
       0.864
Arch_0941
KEGG: xce:Xcel_1345 hypothetical protein; SPTR: D0WMJ0 Putative uncharacterized protein.
       0.854
Arch_0940
COGs: COG0728 membrane protein putative virulence factor; InterPro IPR004268:IPR017441; KEGG: bcv:Bcav_2351 virulence factor MviN family protein; PFAM: virulence factor MVIN family protein; SPTR: D0WMJ1 Putative integral membrane protein MviN; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN.
       0.847
Arch_0939
NUDIX hydrolase; InterPro IPR015797:IPR000086; KEGG: xce:Xcel_1348 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0WMJ2 MutT/NUDIX family protein; PFAM: NUDIX domain.
     
 0.831
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
  
  
 0.826
Arch_0946
COGs: COG1189 rRNA methylase; InterPro IPR002942:IPR004538:IPR002877; KEGG: kra:Krad_3149 hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; SPTR: A7BC42 Putative uncharacterized protein; TIGRFAM: hemolysin A; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein.
 
  
 0.821
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
   
 0.812
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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