STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0959COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR020625:IPR013785:IPR002220; KEGG: ckp:ckrop_1871 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: C0W1Z6 Possible dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase family; Belongs to the DapA family. (305 aa)    
Predicted Functional Partners:
Arch_0961
Oligopeptide/dipeptide ABC transporter, ATPase subunit; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterProIPR010066:IPR003439:IPR000515:IPR017871:IPR 003593:IPR013563; KEGG: ele:Elen_2148 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; binding-protein-dependent transport systems inner membrane component; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: A7BBZ1 Putative uncharacterized protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC trans [...]
 
   
 0.953
nanE
N-acylglucosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
  
 0.896
Arch_0960
ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003439:IPR017871:IPR003593:IPR013563; KEGG: apv:Apar_0932 ABC transporter related; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: A7BBZ2 Putative uncharacterized protein; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region.
 
     0.874
Arch_0963
Extracellular solute-binding protein family 5; COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: ccu:Ccur_06680 ABC-type dipeptide transport system, periplasmic component; PFAM: extracellular solute-binding protein family 5; SPTR: A7BBY9 Putative uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle.
 
   
 0.867
Arch_0962
COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: ele:Elen_2147 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: C2GJT1 ABC superfamily ATP binding cassette transporter, membrane protein; PFAM: Binding-protein-dependent transport system inner membrane component.
 
     0.858
Arch_0026
Exo-alpha-sialidase; COGs: COG4409 Neuraminidase (sialidase); InterPro IPR011040; KEGG: pac:PPA1560 sialidase precursor; PRIAM: Exo-alpha-sialidase; SPTR: Q44562 Sialidase; PFAM: BNR/Asp-box repeat.
 
   
 0.691
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
  
 0.680
Arch_1299
LPXTG-motif cell wall anchor domain protein; COGs: COG4409 Neuraminidase (sialidase); InterPro IPR002860:IPR019931:IPR011040; KEGG: bln:Blon_2348 exo-alpha-sialidase; PFAM: glycosyl hydrolase BNR repeat-containing protein; SPTR: B7GNQ0 Exo-alpha-sialidase; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: BNR/Asp-box repeat.
 
   
 0.666
Arch_0329
Regulatory protein GntR HTH; COGs: COG2186 Transcriptional regulators; InterPro IPR011991:IPR000524:IPR011711; KEGG: bcv:Bcav_3776 regulatory protein GntR HTH; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: D0WKM6 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
   
 0.638
murB
FAD linked oxidase domain protein; Cell wall formation.
     
 0.638
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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