STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0982KEGG: hypothetical protein; SPTR: C1FFK9 Predicted protein. (811 aa)    
Predicted Functional Partners:
Arch_1735
Integrin alpha beta-propellor repeat protein; InterPro IPR013519; KEGG: ITGA1; integrin, alpha 1; K06480 integrin alpha 1; SMART: Integrin alpha beta-propellor repeat protein; SPTR: C2KTJ5 FG-GAP repeat domain protein.
 
 
 
 0.791
Arch_1318
LPXTG-motif cell wall anchor domain protein; COGs: COG1196 Chromosome segregation ATPase; InterPro IPR019931; KEGG: hypothetical protein; SPTR: Q4Q3D8 Putative uncharacterized protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein.
  
     0.695
Arch_1734
Hypothetical protein; InterPro IPR013519; KEGG: hau:Haur_4585 FG-GAP repeat-containing protein; SPTR: D0YPS4 FG-GAP repeat protein; TIGRFAM: LPXTG-motif cell wall anchor domain.
 
 
 
 0.689
Arch_0393
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121:IPR014016:IPR014017:IPR000212; KEGG: bcv:Bcav_2897 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: D0WRX3 ATP-dependent DNA helicase II; PFAM: HRDC domain; UvrD/REP helicase.
  
 
 0.651
Arch_0228
LPXTG-motif cell wall anchor domain protein; InterPro IPR019931; KEGG: cdi:DIP0235 putative fimbrial subunit; SPTR: Q6NK05 Putative fimbrial subunit; TIGRFAM: LPXTG-motif cell wall anchor domain protein; TIGRFAM: LPXTG-motif cell wall anchor domain.
  
    0.554
Arch_0741
Periplasmic binding protein; COGs: COG4594 ABC-type Fe3+-citrate transport system periplasmic component; InterPro IPR002491; KEGG: cdi:DIP0582 putative iron transport system binding (secreted) protein; PFAM: periplasmic binding protein; SPTR: Q6NJ31 Putative iron transport system binding (Secreted) protein; PFAM: Periplasmic binding protein.
  
     0.525
Arch_0628
LPXTG-motif cell wall anchor domain protein; COGs: COG4886 Leucine-rich repeat (LRR) protein; InterPro IPR007331:IPR019931; KEGG: pac:PPA0779 putative for Fe-transport; PFAM: Htaa domain protein; SPTR: C0W1M4 Putative uncharacterized protein; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: Htaa.
 
     0.482
Arch_0877
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.474
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.464
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
   0.434
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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