STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_0990Membrane-flanked domain protein; InterPro IPR005182; KEGG: nfa:nfa9960 hypothetical protein; PFAM: membrane-flanked domain; SPTR: D0WN69 Bacterial membrane flanked domain protein; manually curated; PFAM: Bacterial membrane flanked domain. (166 aa)    
Predicted Functional Partners:
Arch_0991
Hypothetical protein; InterPro IPR011067; KEGG: nca:Noca_3690 hypothetical protein; SPTR: C0W2Y2 Putative uncharacterized protein; PFAM: PemK-like protein.
 
    0.839
Arch_0989
KEGG: hypothetical protein; K01533 Cu2+-exporting ATPase; SPTR: D0WN68 Putative uncharacterized protein.
       0.732
Arch_0737
KEGG: stp:Strop_2530 hypothetical protein; SPTR: D0WQM7 Putative oxidoreductase.
  
     0.604
Arch_0256
Membrane-flanked domain protein; COGs: COG3402 conserved hypothetical protein; InterPro IPR005182; KEGG: rsa:RSal33209_3209 permease; PFAM: membrane-flanked domain; SPTR: A9WUQ5 Permease; PFAM: Bacterial membrane flanked domain.
  
  
 0.541
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.526
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.522
Arch_0986
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
       0.518
Arch_0750
COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterProIPR012337:IPR000305:IPR006055:IPR006054:IPR 013520; KEGG: bcv:Bcav_1900 DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; PRIAM: DNA-directed DNA polymerase; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; SPTR: D0WQL3 Putative DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease; GIY-YIG catalytic domain; TIGRFAM: exonuclease, DNA polymerase III, epsilon subunit family.
 
     0.462
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
       0.456
Arch_1435
VanW family protein; COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391; KEGG: jde:Jden_0796 VanW family protein; PFAM: VanW family protein; SPTR: D0WPN1 VanW like protein; PFAM: Putative peptidoglycan binding domain; VanW like protein.
 
     0.439
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.