STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Arch_1001Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR011146:IPR001310:IPR011151; KEGG: rha:RHA1_ro04743 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: C2BUY1 Histidine triad (HIT) protein; PFAM: HIT domain. (145 aa)    
Predicted Functional Partners:
leuS
COGs: COG0495 Leucyl-tRNA synthetase; InterProIPR009008:IPR009080:IPR002302:IPR001412:IPR 014729:IPR002300:IPR013155; KEGG: bcv:Bcav_1730 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; aminoacyl-tRNA synthetase class Ia; SPTR: D0WN91 Leucine--tRNA ligase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); tRNA synthetases class I (M); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family.
   
   0.639
Arch_0729
COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR014746; KEGG: jde:Jden_1487 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: D0WQP4 Glutamate--ammonia ligase; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
  
   0.575
Arch_0732
COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR014746:IPR004809; KEGG: kra:Krad_3291 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: D0WQN7 Glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
  
   0.575
Arch_0264
ATP-binding protein; COGs: COG0572 Uridine kinase; KEGG: bcv:Bcav_3297 ATP-binding protein; SPTR: C5C1D0 ATP-binding protein.
   
  0.521
udk
COGs: COG0572 Uridine kinase; InterPro IPR006083:IPR000764:IPR017975; KEGG: cbt:CLH_0992 uridine kinase; PFAM: phosphoribulokinase/uridine kinase; SPTR: D0WPE8 Uridine kinase; TIGRFAM: uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: uridine kinase.
   
  0.521
lysS-2
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR016027:IPR002313:IPR006195:IPR012340:IPR 007424:IPR007425:IPR007426:IPR004365:IPR004364:IPR018149; KEGG: cdi:DIP2138 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Q6NEX1 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: Uncharacterized conserved protein (DUF2156); tRNA synthetases class II (D, K and N); OB-fo [...]
   
 0.428
purC
COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636:IPR013816:IPR010916; KEGG: mlu:Mlut_18500 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: D0WLR3 Phosphoribosylaminoimidazolesuccinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase.
   
   0.419
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR020825:IPR005121:IPR016027:IPR009061:IPR 004532:IPR002547:IPR012340:IPR005147:IPR005146; KEGG: jde:Jden_1109 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: D0WN31 Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synt [...]
  
    0.417
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
    0.417
Arch_0254
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.411
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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