STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Arch_1005COGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR000845; KEGG: kse:Ksed_10970 purine-nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; SPTR: C0W1W4 Purine nucleoside phosphorylase; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD). (235 aa)    
Predicted Functional Partners:
Arch_1266
COGs: COG0213 Thymidine phosphorylase; InterProIPR000053:IPR017459:IPR000312:IPR013102:IPR 020072:IPR018090:IPR017872; KEGG: car:cauri_1882 thymidine phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; glycosyl transferase family 3; Glycosyl transferase, family 3-like; PRIAM: Thymidine phosphorylase; SPTR: C3PI21 Thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase.
  
 
 0.941
Arch_1262
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.931
Arch_1267
CMP/dCMP deaminase zinc-binding protein; COGs: COG0295 Cytidine deaminase; InterPro IPR002125:IPR016193:IPR016192; KEGG: sma:SAV_3366 cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: C1YSR4 Cytidine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric.
  
 
 0.927
apt
Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.926
Arch_0769
COGs: COG1435 Thymidine kinase; InterPro IPR001267; KEGG: bcv:Bcav_1932 thymidine kinase; PFAM: thymidine kinase; PRIAM: Thymidine kinase; SPTR: D0WQI6 Thymidine kinase; PFAM: Thymidine kinase.
  
 
 0.925
Arch_1116
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
     
 0.911
Arch_1408
COGs: COG1816 Adenosine deaminase; InterPro IPR001365:IPR006330:IPR013838:IPR006650; KEGG: bcv:Bcav_3173 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: Adenosine deaminase; SPTR: D0WPG6 Adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: Adenosine/AMP deaminase; TIGRFAM: adenosine deaminase.
    
 0.907
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
  0.907
Arch_0239
LPXTG-motif cell wall anchor domain protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334:IPR019931:IPR006179; KEGG: cgt:cgR_0412 hypothetical protein; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; SPTR: D0WQ91 5-nucleotidase; TIGRFAM: LPXTG-motif cell wall anchor domain protein; PFAM: 5'-nucleotidase, C-terminal domain; TIGRFAM: LPXTG-motif cell wall anchor domain.
    
 0.903
Arch_0025
5'-Nucleotidase domain protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR008334:IPR006179; KEGG: mxa:MXAN_5361 putative 5'-nucleotidase; PFAM: 5'-Nucleotidase domain protein; SPTR: A8TK86 5'-Nucleotidase; PFAM: 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
    
  0.902
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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