STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1030Alpha/beta hydrolase fold-3 domain protein; COGs: COG0657 Esterase/lipase; InterPro IPR013094; KEGG: cro:ROD_05341 acetyl esterase; PFAM: Alpha/beta hydrolase fold-3 domain protein; SPTR: D0WP07 Acetyl esterase; PFAM: alpha/beta hydrolase fold. (305 aa)    
Predicted Functional Partners:
Arch_1031
Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR016196:IPR004638:IPR011701:IPR001411; KEGG: krh:KRH_22170 drug resistance efflux protein; PFAM: major facilitator superfamily MFS_1; SPTR: B2GIE2 Drug resistance efflux protein; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily.
       0.782
Arch_1032
InterPro IPR009057:IPR001647:IPR012287; KEGG: mrd:Mrad2831_5885 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: B1M8J9 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
       0.779
crcB
Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.648
crcB-2
Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.648
Arch_0299
NADH-quinone oxidoreductase, chain G; COGs: COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G); InterProIPR001041:IPR019574:IPR006656:IPR010228:IPR 000283; KEGG: xce:Xcel_0475 NADH-quinone oxidoreductase, chain G; PFAM: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; molybdopterin oxidoreductase; SPTR: D0WMG7 NADH dehydrogenase, G subunit; TIGRFAM: NADH-quinone oxidoreductase, chain G; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Molybdopterin oxidoreductase; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; TIG [...]
   
 
 0.607
Arch_0298
NADH-quinone oxidoreductase, F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
    
   0.594
Arch_0297
COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023:IPR005113:IPR012336; KEGG: xce:Xcel_0473 NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; SPTR: D0WMG5 NADH dehydrogenase I, E subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit.
    
   0.585
Arch_1361
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR017871; KEGG: ele:Elen_1832 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: D0WP04 CoA ligase; PFAM: AMP-binding enzyme.
 
 
 0.551
Arch_1362
L-carnitine dehydratase/bile acid-inducible protein F; COGs: COG1804 acyl-CoA transferase/carnitine dehydratase; InterPro IPR003673; KEGG: ele:Elen_1833 L-carnitine dehydratase/bile acid-inducible protein F; PFAM: L-carnitine dehydratase/bile acid-inducible protein F; SPTR: D0WP05 Crotonobetainyl-CoA:carnitine CoA-transferase; PFAM: CoA-transferase family III.
 
  
 0.524
Arch_1360
InterPro IPR002539; KEGG: drm:Dred_0577 dehydratase; PFAM: MaoC domain protein dehydratase; PRIAM:3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-ch olest-24-enoyl-CoAhydratase; SPTR: D0WP03 Putative MaoC like domain protein; PFAM: MaoC like domain.
 
  
 0.520
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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