STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1032InterPro IPR009057:IPR001647:IPR012287; KEGG: mrd:Mrad2831_5885 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: B1M8J9 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family. (206 aa)    
Predicted Functional Partners:
Arch_1030
Alpha/beta hydrolase fold-3 domain protein; COGs: COG0657 Esterase/lipase; InterPro IPR013094; KEGG: cro:ROD_05341 acetyl esterase; PFAM: Alpha/beta hydrolase fold-3 domain protein; SPTR: D0WP07 Acetyl esterase; PFAM: alpha/beta hydrolase fold.
       0.779
Arch_1031
Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR016196:IPR004638:IPR011701:IPR001411; KEGG: krh:KRH_22170 drug resistance efflux protein; PFAM: major facilitator superfamily MFS_1; SPTR: B2GIE2 Drug resistance efflux protein; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily.
  
  
 0.775
crcB
Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.648
crcB-2
Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
       0.648
Arch_0413
InterPro IPR003838; KEGG: bcv:Bcav_2825 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: C5V906 ABC transporter integral membrane protein; PFAM: Predicted permease.
 
   
 0.625
Arch_1180
InterPro IPR009057:IPR001647:IPR012287; KEGG: cjk:jk0810 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: C5VD50 Putative transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family.
  
   
 0.555
Arch_0016
Hypothetical protein; InterPro IPR016181; KEGG: cai:Caci_8064 GCN5-related N-acetyltransferase; SPTR: C0UD33 Acetyltransferase (GNAT) family protein.
  
  
 0.552
Arch_1224
KEGG: xce:Xcel_1029 TadE family protein; SPTR: A1R814 Putative TadE-like family protein.
  
     0.516
pld
Phospholipase D; Virulence factor affecting bacterial dissemination and survival within the host. Has magnesium-dependent catalytic activity toward sphingomyelin (SM) and acyl- and alkyl-lysophosphatidylcholine (LPC), but not toward sphingosylphosphorylcholine (SPC) and phosphatidylcholine (PC). Lysophosphatidic acid (LPA), assumed to result from LPC hydrolysis, evokes pathophysiological responses after LPA receptor internalization. Shows hemolytic activity.
  
     0.512
Arch_0818
COGs: COG2339 membrane protein; KEGG: bcv:Bcav_1985 membrane protein; SPTR: C5C5P9 Membrane protein.
  
    0.486
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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