STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1077COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR003018:IPR011712; KEGG: bcv:Bcav_1613 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: GAF domain protein; ATP-binding region ATPase domain protein; SPTR: D0WNC3 Putative two-component sensor; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain. (544 aa)    
Predicted Functional Partners:
Arch_1076
ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; COGs: COG4987 ABC-type transport system involved in cytochrome bd biosynthesis fused ATPase and permease components; InterProIPR011527:IPR014223:IPR003439:IPR017940:IPR 017871:IPR003593; KEGG: bcv:Bcav_1614 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: C0W2T3 ABC superfamily ATP binding cassette transporter, ABC protein CydC; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family [...]
 
     0.907
Arch_1075
ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; COGs: COG4988 ABC-type transport system involved in cytochrome bd biosynthesis ATPase and permease components; InterProIPR011527:IPR014216:IPR003439:IPR017940:IPR 003593:IPR001140; KEGG: jde:Jden_1656 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: D0WNC1 ABC transporter, CydDC cysteine exporter family, permease/ATP-binding protein CydD; TIGRFAM: ABC trans [...]
 
     0.888
Arch_1078
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR011006:IPR000792:IPR001789:IPR011991; KEGG: jde:Jden_1659 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: D0WNC4 DNA-binding response regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.844
Arch_0529
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR011991:IPR000792:IPR001789:IPR011006:IPR 016032; KEGG: ckp:ckrop_0504 two-component system, response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: D0WNH1 Two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.625
Arch_1074
COGs: COG1294 Cytochrome bd-type quinol oxidase subunit 2; InterPro IPR003317; KEGG: bcv:Bcav_1616 cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; SPTR: D0WNC0 Cytochrome D ubiquinol oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB).
       0.587
Arch_1282
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR000792:IPR001789:IPR011991:IPR011006:IPR 016032; KEGG: jde:Jden_0656 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: C7R1A5 Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.577
Arch_1073
COGs: COG1271 Cytochrome bd-type quinol oxidase subunit 1; InterPro IPR002585; KEGG: xce:Xcel_2267 cytochrome bd ubiquinol oxidase subunit I; PFAM: cytochrome bd ubiquinol oxidase subunit I; SPTR: D0WNB9 Cytochrome D ubiquinol oxidase, subunit I; PFAM: Bacterial Cytochrome Ubiquinol Oxidase.
       0.564
Arch_0526
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR011991:IPR001789:IPR013249:IPR000792:IPR 011006; KEGG: kra:Krad_4263 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; SPTR: D0YQC0 Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.562
Arch_0415
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR011991:IPR000792:IPR001789:IPR011006:IPR 016032; KEGG: bcv:Bcav_2822 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: D0WS35 Two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.560
Arch_0447
InterPro IPR011761; KEGG: jde:Jden_0904 hypothetical protein; SPTR: D0WRH0 Putative uncharacterized protein; PFAM: Prokaryotic glutathione synthetase, ATP-grasp domain.
  
     0.541
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.