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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1082KEGG: bcv:Bcav_1606 hypothetical protein; SPTR: D0WNC7 Putative uncharacterized protein. (168 aa)    
Predicted Functional Partners:
Arch_1081
Protein of unknown function DUF177; COGs: COG1399 metal-binding possibly nucleic acid-binding protein; InterPro IPR003772; KEGG: jde:Jden_1668 protein of unknown function DUF177; PFAM: protein of unknown function DUF177; SPTR: D0WNC6 Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1399.
 
   
 0.891
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
     
 0.874
Arch_1084
Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052:IPR016065; KEGG: kra:Krad_1371 putative methyltransferase; PFAM: Protein of unknown function methylase putative; SPTR: A7BCZ1 Putative uncharacterized protein; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family.
  
    0.828
Arch_1085
DEAD/DEAH box helicase domain protein; COGs: COG1200 RecG-like helicase; InterProIPR016027:IPR014021:IPR001650:IPR014001:IPR 004365:IPR011545; KEGG: xce:Xcel_2279 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D0WND1 Putative ATP-dependent DNA helicase RecG; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; OB-fold nucleic acid binding domain; TIGRFAM: ATP-dependent DNA helicase RecG.
       0.801
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
     
 0.796
Arch_0102
COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635:IPR002290:IPR005543:IPR017442:IPR 005503:IPR000719:IPR011009:IPR017441:IPR008271; KEGG: xce:Xcel_0018 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; flagellar basal body-associated protein FliL; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; PASTA domain containing protein; SPTR: D0WKX3 Putative serine/threonine protein kinase; PFAM: Protein kinase domain; PASTA domain.
 
 
 0.739
Arch_0754
Serine/threonine protein kinase with PASTA sensor(s); COGs: COG2815 conserved hypothetical protein; InterProIPR011009:IPR008271:IPR020635:IPR002290:IPR 005543:IPR000719:IPR017442; KEGG: bcv:Bcav_1908 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; PASTA domain containing protein; SPTR: A7BDG0 Putative uncharacterized protein; PFAM: Protein kinase domain; PASTA domain.
 
 
 0.707
Arch_1079
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
     
 0.674
Arch_1727
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR012338:IPR005543:IPR001264:IPR001460; KEGG: bcv:Bcav_0604 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PASTA domain containing protein; PRIAM: Peptidoglycan glycosyltransferase; SPTR: D0WK60 Penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; PASTA domain.
   
 
 0.551
Arch_1803
Peptidoglycan glycosyltransferase; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR012338:IPR001264:IPR001460; KEGG: bcv:Bcav_4182 glycosyl transferase family 51; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: D0WL42 Penicillin-binding protein; manually curated; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase.
   
 
 0.551
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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