STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (158 aa)    
Predicted Functional Partners:
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
    
 0.982
Arch_0855
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
  
 0.976
coaA
COGs: COG1072 Panthothenate kinase; InterPro IPR004566; KEGG: xce:Xcel_0666 pantothenate kinase; SPTR: A7B9K0 Putative uncharacterized protein; TIGRFAM: pantothenate kinase; PFAM: Phosphoribulokinase / Uridine kinase family; TIGRFAM: pantothenate kinase, bacterial type.
     
 0.975
Arch_1084
Methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052:IPR016065; KEGG: kra:Krad_1371 putative methyltransferase; PFAM: Protein of unknown function methylase putative; SPTR: A7BCZ1 Putative uncharacterized protein; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family.
 
  
 0.972
Arch_1082
KEGG: bcv:Bcav_1606 hypothetical protein; SPTR: D0WNC7 Putative uncharacterized protein.
     
 0.874
Arch_1085
DEAD/DEAH box helicase domain protein; COGs: COG1200 RecG-like helicase; InterProIPR016027:IPR014021:IPR001650:IPR014001:IPR 004365:IPR011545; KEGG: xce:Xcel_2279 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: D0WND1 Putative ATP-dependent DNA helicase RecG; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; OB-fold nucleic acid binding domain; TIGRFAM: ATP-dependent DNA helicase RecG.
       0.837
Arch_1079
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
     
 0.763
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.746
Arch_1081
Protein of unknown function DUF177; COGs: COG1399 metal-binding possibly nucleic acid-binding protein; InterPro IPR003772; KEGG: jde:Jden_1668 protein of unknown function DUF177; PFAM: protein of unknown function DUF177; SPTR: D0WNC6 Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1399.
       0.737
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
   
 0.727
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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