STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Arch_1096COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: sco:SCO2132 glycosyl transferase; PFAM: glycosyl transferase group 1; SPTR: D0WNF3 Glycosyl transferase; PFAM: Glycosyl transferases group 1. (377 aa)    
Predicted Functional Partners:
Arch_1095
Transcriptional regulator, IclR family; COGs: COG1414 Transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: xce:Xcel_2358 transcriptional regulator, IclR family; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: D1BVQ5 Transcriptional regulator, IclR family; manually curated; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator.
       0.790
Arch_0393
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR002121:IPR014016:IPR014017:IPR000212; KEGG: bcv:Bcav_2897 UvrD/REP helicase; PFAM: UvrD/REP helicase; HRDC domain protein; SMART: HRDC domain protein; SPTR: D0WRX3 ATP-dependent DNA helicase II; PFAM: HRDC domain; UvrD/REP helicase.
    
 
 0.718
Arch_0800
Malto-oligosyltrehalose trehalohydrolase; COGs: COG0296 1 4-alpha-glucan branching enzyme; InterProIPR017853:IPR014756:IPR006589:IPR012768:IPR 013783:IPR013781:IPR004193:IPR006047; KEGG: bcv:Bcav_1971 malto-oligosyltrehalose trehalohydrolase; PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein; SMART: alpha amylase catalytic sub domain; SPTR: C5C5N5 Malto-oligosyltrehalose trehalohydrolase; TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: Alpha amylase, catalytic domain; TIGRFAM: malto-oligosyltrehalose trehalohydrolase.
   
 0.685
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
 0.662
dcp
Peptidyl-dipeptidase Dcp; COGs: COG0339 Zn-dependent oligopeptidase; InterPro IPR001567; KEGG: bcv:Bcav_2254 peptidyl-dipeptidase DCP; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; PRIAM: Peptidyl-dipeptidase Dcp; SPTR: C7SZ49 Peptidyl-dipeptidase; PFAM: Peptidase family M3.
  
    0.614
Arch_0388
Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 
 0.596
murA
UDP-N-acetylglucosamine1- carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
     
 0.532
Arch_1093
COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: art:Arth_2516 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: D0WNE3 1-acylglycerol-3-phosphate O-acyltransferase, putayive; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
  
    0.470
Arch_1633
KEGG: sgr:SGR_4058 hypothetical protein; SPTR: B1VSD3 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3263).
  
     0.462
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
     0.453
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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