STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1115ATP-dependent Clp protease adaptor protein ClpS; COGs: COG2127 conserved hypothetical protein; InterPro IPR014719:IPR003769; KEGG: sco:SCO2916 ATP-dependent Clp protease adaptor protein ClpS; PFAM: ATP-dependent Clp protease adaptor protein ClpS; SPTR: C4DNG9 Uncharacterized conserved protein, COG2127; PFAM: ATP-dependent Clp protease adaptor protein ClpS. (100 aa)    
Predicted Functional Partners:
Arch_1114
Domain of unknown function DUF2017; InterPro IPR018561; KEGG: bcv:Bcav_2740 hypothetical protein; PFAM: Domain of unknown function DUF2017; SPTR: D0WNI6 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF2017).
 
  
 0.896
Arch_1466
COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR002177:IPR008331:IPR012347:IPR009078; KEGG: pac:PPA2134 starvation-inducible DNA-binding protein or fine tangled pili major subunit; PFAM: Ferritin Dps family protein; SPTR: A7BBG2 Putative uncharacterized protein; PFAM: Ferritin-like domain; Belongs to the Dps family.
   
 
 0.893
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.888
Arch_0227
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR004176:IPR003959:IPR001943:IPR 013093:IPR019489:IPR001270:IPR018368; KEGG: xce:Xcel_0363 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: D0WM50 Negative regulator of genetic competence ClpC/MecB; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various c [...]
  
 
 0.888
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.862
Arch_1112
Beta-lactamase domain protein; COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: bcv:Bcav_2736 beta-lactamase domain protein; SPTR: D0WNI4 Metal-dependent hydrolase of the beta-lactamase superfamily III; PFAM: Metallo-beta-lactamase superfamily.
       0.845
clpP-2
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.683
Arch_1116
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
     
 0.646
whiB-3
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.644
clpP
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
 
 0.619
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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