STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1117Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014021:IPR014001:IPR006935; KEGG: art:Arth_2588 type III restriction enzyme, res subunit; PFAM: type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: D0WNJ0 Putative DNA or RNA helicase of superfamily II; PFAM: Type III restriction enzyme, res subunit. (595 aa)    
Predicted Functional Partners:
Arch_1118
KEGG: bcv:Bcav_2744 hypothetical protein; SPTR: D0WNJ1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3039).
 
     0.882
Arch_0655
Helicase c2; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR014001:IPR006555:IPR014013; KEGG: xce:Xcel_1256 helicase C2; SMART: helicase c2; DEAD-like helicase; SPTR: D0WQY5 ATP-dependent helicase DinG.
   
 0.837
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.785
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.784
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.780
Arch_0984
KEGG: aau:AAur_2236 hypothetical protein; SPTR: D0WN61 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3097).
  
     0.759
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.705
Arch_1705
Methyltransferase small; COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR002052:IPR007848; KEGG: kse:Ksed_25140 methyltransferase family protein; PFAM: methyltransferase small; SPTR: C7NG68 Methyltransferase family protein; PFAM: Methyltransferase small domain; Belongs to the methyltransferase superfamily.
 
 
   0.621
Arch_0830
InterPro IPR007139; KEGG: bcv:Bcav_2001 protein of unknown function DUF349; PFAM: protein of unknown function DUF349; SPTR: C5C5R5 Putative uncharacterized protein; PFAM: Domain of Unknown Function (DUF349).
 
  
 0.617
nucS
Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
 
     0.580
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.