STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1121COGs: COG0627 esterase; InterPro IPR000801; KEGG: cgt:cgR_1064 hypothetical protein; PFAM: putative esterase; SPTR: C2KS46 Esterase; PFAM: Putative esterase. (424 aa)    
Predicted Functional Partners:
Arch_0038
Alcohol dehydrogenase zinc-binding domain protein; COGs: COG1062 Zn-dependent alcohol dehydrogenase class III; InterPro IPR013154:IPR013149:IPR011032:IPR016040; KEGG: hypothetical protein; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: D0YPM1 Alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
  
 
 0.916
Arch_1016
KEGG: cdi:DIP2140 putative integral membrane protein; SPTR: Q6NEW9 Putative integral membrane protein; manually curated.
  
   
 0.662
Arch_1671
Protein of unknown function DUF156; COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: cdi:DIP1749 hypothetical protein; PFAM: protein of unknown function DUF156; SPTR: Q6NFY6 Putative uncharacterized protein; PFAM: Uncharacterised BCR, COG1937.
  
  
 0.613
Arch_1120
YidE/YbjL duplication; COGs: COG2985 permease; InterPro IPR016040:IPR006512:IPR006037:IPR017871; KEGG: bfa:Bfae_01390 predicted permease; PFAM: YidE/YbjL duplication domain protein; TrkA-C domain protein; SPTR: D0YRM3 YidE/YbjL duplication; TIGRFAM: YidE/YbjL duplication; PFAM: Predicted Permease Membrane Region; TrkA-C domain; TIGRFAM: YidE/YbjL duplication.
       0.550
Arch_0413
InterPro IPR003838; KEGG: bcv:Bcav_2825 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: C5V906 ABC transporter integral membrane protein; PFAM: Predicted permease.
  
   
 0.544
lysS-2
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR016027:IPR002313:IPR006195:IPR012340:IPR 007424:IPR007425:IPR007426:IPR004365:IPR004364:IPR018149; KEGG: cdi:DIP2138 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Q6NEX1 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: Uncharacterized conserved protein (DUF2156); tRNA synthetases class II (D, K and N); OB-fo [...]
 
   
 0.540
Arch_0010
Coagulation factor 5/8 type domain protein; COGs: COG1196 Chromosome segregation ATPase; InterPro IPR000421:IPR008979; KEGG: cai:Caci_5658 ricin B lectin; PFAM: coagulation factor 5/8 type domain protein; SPTR: C7QC69 Ricin B lectin; PFAM: F5/8 type C domain.
  
     0.526
pld
Phospholipase D; Virulence factor affecting bacterial dissemination and survival within the host. Has magnesium-dependent catalytic activity toward sphingomyelin (SM) and acyl- and alkyl-lysophosphatidylcholine (LPC), but not toward sphingosylphosphorylcholine (SPC) and phosphatidylcholine (PC). Lysophosphatidic acid (LPA), assumed to result from LPC hydrolysis, evokes pathophysiological responses after LPA receptor internalization. Shows hemolytic activity.
  
     0.501
Arch_1796
COGs: COG4932 outer membrane protein; InterPro IPR008454; KEGG: soz:Spy49_0112 putative collagen binding protein; PFAM: Cna B domain protein; SPTR: B5XJF1 Putative collagen binding protein; TIGRFAM: LPXTG-motif cell wall anchor domain.
  
     0.500
Arch_0254
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
       0.493
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.