STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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Textmining
[Homology]
Score
Arch_1123Dihydroxyacetone kinase, DhaK subunit; COGs: COG2376 Dihydroxyacetone kinase; InterPro IPR004007:IPR012736:IPR012737:IPR004006; KEGG: msm:MSMEG_2123 dihydroxyacetone kinase, DhaK subunit; PFAM: Dak kinase; Dak phosphatase; PRIAM: Glycerone kinase; SPTR: A0QU93 Dihydroxyacetone kinase, DhaK subunit; TIGRFAM: dihydroxyacetone kinase, DhaK subunit; dihydroxyacetone kinase, L subunit; PFAM: DAK2 domain; Dak1 domain; TIGRFAM: dihydroxyacetone kinase, ATP-dependent; dihydroxyacetone kinase, DhaK subunit; dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. (580 aa)    
Predicted Functional Partners:
Arch_1122
Dihydroxyacetone kinase, phosphotransfer subunit; COGs: COG3412 conserved hypothetical protein; InterProIPR000032:IPR004701:IPR012844:IPR005698:IPR 001020; KEGG: ecm:EcSMS35_4856 phosphoenolpyruvate-protein phosphotransferase PtnE; PFAM: PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; SPTR: D0YPG5 PTS-dependent dihydroxyacetone kinase, DhaM subunit; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; PFAM: PTS system fructose IIA component; PTS HPr component phosphorylation site; TIGRFAM: dihydroxyacetone kinase, phosphotr [...]
 
 0.999
Arch_0556
Dihydroxyacetone kinase, L subunit; COGs: COG2376 Dihydroxyacetone kinase; InterPro IPR004007:IPR012737; KEGG: car:cauri_1454 dihydroxyacetone kinase; PFAM: Dak phosphatase; SPTR: A7BCU2 Putative uncharacterized protein; TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: DAK2 domain; TIGRFAM: dihydroxyacetone kinase, phosphoprotein-dependent, L subunit.
 
  
0.928
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.925
Arch_0192
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.909
Arch_1733
Transcriptional regulator, DeoR family; COGs: COG2390 Transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR009057:IPR007324; KEGG: krh:KRH_18930 deoxyribonucleoside regulator; PFAM: putative sugar-binding domain protein; SPTR: C0W0V8 DeoR family transcriptional regulator; PFAM: Putative sugar-binding domain.
     0.854
Arch_0267
Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR006076:IPR007419:IPR017752:IPR000447; KEGG: pac:PPA2250 anaerobic glycerol-3-phosphate dehydrogenase subunit A; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: D0YR89 Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit.
    
 0.828
Arch_0266
Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; COGs: COG3075 Anaerobic glycerol-3-phosphate dehydrogenase; InterPro IPR003953:IPR009158; KEGG: pac:PPA2249 anaerobic glycerol-3-phosphate dehydrogenase subunit B; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: D0YR90 Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; PFAM: FAD binding domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit.
    
  0.802
Arch_0265
Glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; COGs: COG0247 Fe-S oxidoreductase; InterProIPR001450:IPR004017:IPR012285:IPR017896:IPR 017753:IPR009051:IPR017900; KEGG: pac:PPA2248 sn-glycerol-3-phosphate dehydrogenase subunit C; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C2BV29 sn-glycerol-3-phosphate dehydrogenase subunit C; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; PFAM: Cysteine-rich domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit.
     
  0.800
Arch_1124
Protein of unknown function UPF0118; COGs: COG0628 permease; InterPro IPR002549; KEGG: bcv:Bcav_2286 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: C5BVF0 Putative uncharacterized protein; PFAM: Domain of unknown function DUF20.
       0.489
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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