STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1140COGs: COG0311 glutamine amidotransferase involved in pyridoxine biosynthesis; InterPro IPR002161; KEGG: dsy:DSY4245 glutamine amidotransferase subunit PdxT; PFAM: SNO glutamine amidotransferase; SPTR: D0WI52 Glutamine amidotransferase subunit PdxT; PFAM: SNO glutamine amidotransferase family. (210 aa)    
Predicted Functional Partners:
pdxS
Pyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
 0.999
Arch_0468
COGs: COG1946 Acyl-CoA thioesterase; InterPro IPR003703; KEGG: bcv:Bcav_2638 palmitoyl-CoA hydrolase; PFAM: acyl-CoA thioesterase; SPTR: D0WRE2 Acyl-CoA thioesterase II; PFAM: Acyl-CoA thioesterase; TIGRFAM: acyl-CoA thioesterase II.
     
 0.555
Arch_0820
Protein of unknown function DUF28; COGs: COG0217 conserved hypothetical protein; InterPro IPR002876:IPR017856; KEGG: ami:Amir_2110 protein of unknown function DUF28; PFAM: protein of unknown function DUF28; SPTR: D0WQF1 Protein YebC; PFAM: Domain of unknown function DUF28; TIGRFAM: conserved hypothetical protein TIGR01033.
     
 0.542
gatC
glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
     
  0.500
gatA
glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
     
  0.500
gatB
glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
     
  0.500
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.473
Arch_1139
KEGG: bra:BRADO3971 hypothetical protein; SPTR: A4YV00 Putative uncharacterized protein.
       0.464
Arch_1142
Metal dependent phosphohydrolase; COGs: COG1418 HD superfamily hydrolase; InterPro IPR003607:IPR006674; KEGG: lsa:LSA1145 putative metal-dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Q38WI6 Putative metal-dependent phosphohydrolase; PFAM: HD domain.
       0.451
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.