STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Arch_1164Galactokinase; COGs: COG0153 Galactokinase; InterProIPR020568:IPR000705:IPR019741:IPR006203:IPR 014721:IPR019539:IPR006204:IPR013750:IPR006206; KEGG: nca:Noca_2607 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: A1SJX6 Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Belongs to the GHMP kinase family. GalK subfamily. (378 aa)    
Predicted Functional Partners:
galT
COGs: COG4468 Galactose-1-phosphate uridyltransferase; InterPro IPR005849:IPR005850; KEGG: blo:BL1643 galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein; PRIAM: UDP-glucose--hexose-1-phosphate uridylyltransferase; SPTR: Q8G3W0 Galactose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 2.
 
 
 0.994
Arch_0999
Aldose 1-epimerase; COGs: COG2017 Galactose mutarotase; InterPro IPR011013:IPR014718:IPR008183; KEGG: ara:Arad_14113 aldose epimerase; PFAM: Aldose 1-epimerase; SPTR: D0WN90 Putative aldose epimerase; PFAM: Aldose 1-epimerase.
  
 0.983
Arch_0162
Conserved hypothetical protein; COGs: COG1085 Galactose-1-phosphate uridylyltransferase; InterPro IPR011146:IPR000169; KEGG: cef:CE1985 hypothetical protein; SPTR: D0WKB8 UTP--hexose-1-phosphate uridylyltransferase.
  
 
 0.964
Arch_1167
COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR016040:IPR005886:IPR001509:IPR008089; KEGG: blj:BLD_1768 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: B9TTH2 GalE1; TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
 
 0.960
Arch_1292
LPXTG-motif cell wall anchor domain protein; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterProIPR000421:IPR006104:IPR006102:IPR006103:IPR 011081:IPR011080:IPR013781:IPR019931:IPR017853:IPR008979:I PR006101; KEGG: apv:Apar_0102 glycoside hydrolase family 2 sugar binding; PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; Ig domain protein; coagulation factor 5/8 type domain protein; SPTR: A4K5H9 Beta-galactosidase BbgIII; TIGRFAM: LPXTG-motif cell wall anchor dom [...]
 
  
 0.744
Arch_0949
KEGG: jde:Jden_1121 hypothetical protein; SPTR: C7R3S0 Putative uncharacterized protein.
   
 
 0.686
Arch_1458
PTS system, glucose subfamily, IIA subunit; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR001127:IPR001996:IPR013013:IPR018113:IPR 003352:IPR011055; KEGG: cdi:DIP1151 PTS system, glucose-specific IIABC component; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: C2CRZ1 Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; TIGRFAM: PTS system, glucose subfamil [...]
   
  
 0.669
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
      
 0.616
atpD
ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
    
   0.591
Arch_1162
FMN-binding domain protein; InterPro IPR007329; KEGG: fra:Francci3_0232 FMN-binding; PFAM: FMN-binding domain protein; SPTR: C5NUC0 FMN-binding; PFAM: FMN-binding domain.
       0.568
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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