STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Arch_1219Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (304 aa)    
Predicted Functional Partners:
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
 
 
 0.999
Arch_1218
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR011055:IPR016047; KEGG: bcv:Bcav_2767 peptidase M23; PFAM: Peptidase M23; SPTR: D0WNL6 Putative M23 peptidase domain protein; PFAM: Peptidase family M23.
 
  
 0.909
Arch_0246
NLP/P60 protein; COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: blt:Balat_0454 cell wall-associated hydrolase; PFAM: NLP/P60 protein; SPTR: D0WMB9 Putative NLP/P60 family protein; PFAM: NlpC/P60 family.
 
 
 0.847
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
  
  
 0.832
Arch_1617
NLP/P60 protein; COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR006162:IPR000064; KEGG: bcv:Bcav_0883 NLP/P60 protein; PFAM: NLP/P60 protein; SPTR: C0W426 NLP/P60 family protein; PFAM: NlpC/P60 family.
 
 
 0.828
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
     
 0.700
Arch_1223
KEGG: xce:Xcel_1028 TadE family protein; SPTR: D1BYY4 TadE family protein.
 
     0.622
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.617
Arch_1224
KEGG: xce:Xcel_1029 TadE family protein; SPTR: A1R814 Putative TadE-like family protein.
     
 0.574
Arch_1225
KEGG: kse:Ksed_10350 hypothetical protein; SPTR: A4AK55 Putative uncharacterized protein.
       0.563
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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