STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1222KEGG: kra:Krad_3784 hypothetical protein; SPTR: A6WEK8 Putative uncharacterized protein. (138 aa)    
Predicted Functional Partners:
Arch_1223
KEGG: xce:Xcel_1028 TadE family protein; SPTR: D1BYY4 TadE family protein.
       0.822
Arch_1224
KEGG: xce:Xcel_1029 TadE family protein; SPTR: A1R814 Putative TadE-like family protein.
       0.822
Arch_1225
KEGG: kse:Ksed_10350 hypothetical protein; SPTR: A4AK55 Putative uncharacterized protein.
       0.815
Arch_1227
Type II secretion system F domain protein; COGs: COG4965 Flp pilus assembly protein TadB; InterPro IPR018076; KEGG: xce:Xcel_1032 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: D1BYY8 Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain.
     
 0.779
prfB
Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
       0.778
Arch_1226
InterPro IPR018076; KEGG: bcv:Bcav_2789 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: C5BYD4 Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain.
       0.758
Arch_1228
Type II secretion system protein E; COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482; KEGG: fra:Francci3_0779 type II secretion system protein E; PFAM: type II secretion system protein E; SPTR: A3TG68 Putative type II/type IV pathway secretion protein; PFAM: Type II/IV secretion system protein.
     
 0.743
Arch_1219
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.554
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.554
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.530
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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