close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1236PHP domain protein; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR016195:IPR003141:IPR004013; KEGG: jde:Jden_0704 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: D0WNN5 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; PFAM: PHP domain. (278 aa)    
Predicted Functional Partners:
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
      0.896
Arch_1235
Multiple antibiotic resistance (MarC)-related protein; COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: cai:Caci_8100 multiple antibiotic resistance (MarC)-related protein; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: D0YNY9 Membrane protein; PFAM: MarC family integral membrane protein; TIGRFAM: conserved hypothetical protein TIGR00427.
       0.822
Arch_1237
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131:IPR007865; KEGG: bcv:Bcav_2910 peptidase M24; PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; SPTR: D0WNN6 Xaa-Pro aminopeptidase I; PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24; Belongs to the peptidase M24B family.
 
     0.712
Arch_1238
MgtE intracellular region; COGs: COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); InterPro IPR011002:IPR000644:IPR006668; KEGG: bcv:Bcav_2913 MgtE intracellular region; PFAM: MgtE intracellular region; CBS domain containing protein; SPTR: D0WNN7 Putative magnesium transporter MgtE; PFAM: MgtE intracellular N domain; CBS domain.
       0.501
Arch_1239
Protein of unknown function DUF1003; COGs: COG4420 membrane protein; InterPro IPR010406; KEGG: xce:Xcel_0765 protein of unknown function DUF1003; PFAM: protein of unknown function DUF1003; SPTR: C0W117 Integral membrane protein; PFAM: Protein of unknown function (DUF1003).
       0.501
Arch_1240
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.501
Arch_0254
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
       0.493
Arch_0714
Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR017945:IPR006070:IPR004388; KEGG: bfa:Bfae_12460 translation factor SUA5; PFAM: SUA5/yciO/yrdC domain; SPTR: D0WQR0 Sua5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family.
 
    0.488
Arch_1241
COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: bcv:Bcav_2922 O-methyltransferase family 3; PFAM: O-methyltransferase family 3; SPTR: D0WNP0 O-methyltransferase; PFAM: O-methyltransferase.
       0.428
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.