STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1237Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131:IPR007865; KEGG: bcv:Bcav_2910 peptidase M24; PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; SPTR: D0WNN6 Xaa-Pro aminopeptidase I; PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24; Belongs to the peptidase M24B family. (502 aa)    
Predicted Functional Partners:
Arch_1236
PHP domain protein; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR016195:IPR003141:IPR004013; KEGG: jde:Jden_0704 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: D0WNN5 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; PFAM: PHP domain.
 
     0.712
Arch_1239
Protein of unknown function DUF1003; COGs: COG4420 membrane protein; InterPro IPR010406; KEGG: xce:Xcel_0765 protein of unknown function DUF1003; PFAM: protein of unknown function DUF1003; SPTR: C0W117 Integral membrane protein; PFAM: Protein of unknown function (DUF1003).
 
     0.710
Arch_1240
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
   0.692
Arch_1238
MgtE intracellular region; COGs: COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); InterPro IPR011002:IPR000644:IPR006668; KEGG: bcv:Bcav_2913 MgtE intracellular region; PFAM: MgtE intracellular region; CBS domain containing protein; SPTR: D0WNN7 Putative magnesium transporter MgtE; PFAM: MgtE intracellular N domain; CBS domain.
       0.662
Arch_1179
COGs: COG0516 IMP dehydrogenase/GMP reductase; InterProIPR005991:IPR018529:IPR000644:IPR013785:IPR 001093; KEGG: sco:SCO1461 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; PRIAM: IMP dehydrogenase; SMART: CBS domain containing protein; SPTR: C0W4C2 Possible IMP dehydrogenase; TIGRFAM: IMP dehydrogenase family protein; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; IMP dehydrogenase family protein.
   
   0.645
Arch_0473
COGs: COG0308 Aminopeptidase N; InterPro IPR014782:IPR012778; KEGG: bcv:Bcav_2630 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: D0WRD5 Aminopeptidase; TIGRFAM: aminopeptidase N; PFAM: Domain of unknown function (DUF3358); Peptidase family M1; TIGRFAM: aminopeptidase N, Streptomyces lividans type.
 
 
 0.623
Arch_1235
Multiple antibiotic resistance (MarC)-related protein; COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: cai:Caci_8100 multiple antibiotic resistance (MarC)-related protein; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: D0YNY9 Membrane protein; PFAM: MarC family integral membrane protein; TIGRFAM: conserved hypothetical protein TIGR00427.
       0.621
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
      
 0.620
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.612
Arch_0872
COGs: COG0308 Aminopeptidase N; InterPro IPR014782:IPR016059:IPR012778; KEGG: kse:Ksed_24070 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: C7NFC1 Aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Peptidase family M1; Domain of unknown function (DUF3358); TIGRFAM: aminopeptidase N, Streptomyces lividans type.
 
 
 0.611
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.