STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1238MgtE intracellular region; COGs: COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); InterPro IPR011002:IPR000644:IPR006668; KEGG: bcv:Bcav_2913 MgtE intracellular region; PFAM: MgtE intracellular region; CBS domain containing protein; SPTR: D0WNN7 Putative magnesium transporter MgtE; PFAM: MgtE intracellular N domain; CBS domain. (429 aa)    
Predicted Functional Partners:
Arch_1239
Protein of unknown function DUF1003; COGs: COG4420 membrane protein; InterPro IPR010406; KEGG: xce:Xcel_0765 protein of unknown function DUF1003; PFAM: protein of unknown function DUF1003; SPTR: C0W117 Integral membrane protein; PFAM: Protein of unknown function (DUF1003).
 
     0.958
Arch_1240
ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.857
Arch_1241
COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: bcv:Bcav_2922 O-methyltransferase family 3; PFAM: O-methyltransferase family 3; SPTR: D0WNP0 O-methyltransferase; PFAM: O-methyltransferase.
 
     0.786
Arch_1237
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131:IPR007865; KEGG: bcv:Bcav_2910 peptidase M24; PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; SPTR: D0WNN6 Xaa-Pro aminopeptidase I; PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24; Belongs to the peptidase M24B family.
       0.658
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.521
Arch_1235
Multiple antibiotic resistance (MarC)-related protein; COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: cai:Caci_8100 multiple antibiotic resistance (MarC)-related protein; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: D0YNY9 Membrane protein; PFAM: MarC family integral membrane protein; TIGRFAM: conserved hypothetical protein TIGR00427.
       0.485
Arch_1236
PHP domain protein; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR016195:IPR003141:IPR004013; KEGG: jde:Jden_0704 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: D0WNN5 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; PFAM: PHP domain.
       0.484
trmD
tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
     
 0.431
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
   
 0.403
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.