STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Arch_1240ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (374 aa)    
Predicted Functional Partners:
Arch_1238
MgtE intracellular region; COGs: COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); InterPro IPR011002:IPR000644:IPR006668; KEGG: bcv:Bcav_2913 MgtE intracellular region; PFAM: MgtE intracellular region; CBS domain containing protein; SPTR: D0WNN7 Putative magnesium transporter MgtE; PFAM: MgtE intracellular N domain; CBS domain.
       0.857
Arch_1239
Protein of unknown function DUF1003; COGs: COG4420 membrane protein; InterPro IPR010406; KEGG: xce:Xcel_0765 protein of unknown function DUF1003; PFAM: protein of unknown function DUF1003; SPTR: C0W117 Integral membrane protein; PFAM: Protein of unknown function (DUF1003).
       0.857
Arch_0932
SUF system FeS assembly protein, NifU family; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR011341:IPR002871; KEGG: blt:Balat_0915 hypothetical protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: D0WMJ9 SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family.
  
  
 0.845
Arch_1241
COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: bcv:Bcav_2922 O-methyltransferase family 3; PFAM: O-methyltransferase family 3; SPTR: D0WNP0 O-methyltransferase; PFAM: O-methyltransferase.
       0.819
miaB
RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
  
  
 0.767
Arch_1237
Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131:IPR007865; KEGG: bcv:Bcav_2910 peptidase M24; PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; SPTR: D0WNN6 Xaa-Pro aminopeptidase I; PFAM: Aminopeptidase P, N-terminal domain; Metallopeptidase family M24; Belongs to the peptidase M24B family.
  
   0.694
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
  
 0.693
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
 0.682
Arch_0746
Iron-sulfur cluster assembly accessory protein; COGs: COG0316 conserved hypothetical protein; InterPro IPR000361:IPR017870:IPR016092; KEGG: lxx:Lxx15060 hypothetical protein; PFAM: HesB/YadR/YfhF-family protein; SPTR: Q6AE82 Putative uncharacterized protein; TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
 
 
 0.670
nuoD
NADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
  
 0.669
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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