STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Arch_1247Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (403 aa)    
Predicted Functional Partners:
Arch_1249
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR003448:IPR001453; KEGG: xce:Xcel_1817 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin biosynthesis MoaE protein; molybdopterin binding domain; SPTR: D0WL91 Molybdopterin converting factor, subunit 2; PFAM: Probable molybdopterin binding domain; MoaE protein; TIGRFAM: molybdenum cofactor synthesis domain.
 
 
 0.971
Arch_1246
COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: car:cauri_1058 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin cofactor biosynthesis MoaC region; SPTR: A7BBB8 Putative uncharacterized protein; TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
 
  
 0.953
Arch_0406
COGs: COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A; InterPro IPR002052; KEGG: pac:PPA0512 putative molybdopterin-guanine dinucleotide biosynthesis protein A; SPTR: C2BVS3 Molybdopterin-guanine dinucleotide biosynthesis protein.
 
 0.934
Arch_1609
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
  
 
0.922
Arch_1248
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR009036:IPR016040:IPR000594:IPR007901; KEGG: ach:Achl_2496 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: B8HBS3 UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family.
 
  
 0.887
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.887
Arch_1244
Molybdenum ABC transporter, periplasmic molybdate-binding protein; COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR005950:IPR006059; KEGG: pac:PPA0504 putative molybdate-binding protein precursor; PFAM: extracellular solute-binding protein family 1; SPTR: Q6AAF9 Putative molybdate-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: Substrate binding domain of ABC-type glycine betaine transport system; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein.
 
 
 0.696
Arch_0493
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453:IPR008284; KEGG: tfu:Tfu_0376 molybdopterin adenylyltransferase; PFAM: molybdopterin binding domain; SPTR: Q47T03 Molybdopterin adenylyltransferase; PFAM: Probable molybdopterin binding domain.
 
 
 0.651
Arch_1245
NifC-like ABC-type porter; COGs: COG4149 ABC-type molybdate transport system permease component; InterProIPR006469:IPR011867:IPR003439:IPR000515:IPR 003593; KEGG: sgr:SGR_3501 putative ABC transporter ATPase and permease component; PFAM: ABC transporter related; binding-protein-dependent transport systems inner membrane component; SMART: AAA ATPase; SPTR: A7BBD7 Putative uncharacterized protein; TIGRFAM: NifC-like ABC-type porter; molybdate ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter; TIGRFAM: molyb [...]
  
 
 0.622
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
 
      0.433
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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