STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Arch_1248UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR009036:IPR016040:IPR000594:IPR007901; KEGG: ach:Achl_2496 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: B8HBS3 UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family. (239 aa)    
Predicted Functional Partners:
Arch_1249
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR003448:IPR001453; KEGG: xce:Xcel_1817 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin biosynthesis MoaE protein; molybdopterin binding domain; SPTR: D0WL91 Molybdopterin converting factor, subunit 2; PFAM: Probable molybdopterin binding domain; MoaE protein; TIGRFAM: molybdenum cofactor synthesis domain.
 0.983
Arch_1250
thiamineS protein; InterPro IPR016155:IPR012675:IPR003749; KEGG: fre:Franean1_6174 thiamineS protein; PFAM: thiamineS protein; SPTR: D0WL89 Molybdopterin converting factor, subunit 1; PFAM: ThiS family.
  
 0.982
Arch_1278
Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004305:IPR016084:IPR004399; KEGG: pac:PPA0110 thiamine-phosphate pyrophosphorylase; PFAM: Phosphomethylpyrimidine kinase type-1; TENA/THI-4 domain protein; SPTR: Q6ABQ9 Putative thiamine biosynthesis protein; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TENA/THI-4/PQQC family; TIGRFAM: phosphomethylpyrimidine kinase.
 
  
 0.974
Arch_1247
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.887
Arch_1246
COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: car:cauri_1058 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin cofactor biosynthesis MoaC region; SPTR: A7BBB8 Putative uncharacterized protein; TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
 
   
 0.861
Arch_0254
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.777
Arch_1492
KEGG: dps:DP0242 hypothetical protein; SPTR: A6E5J8 Putative uncharacterized protein.
  
   0.746
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.710
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR020825:IPR005121:IPR016027:IPR009061:IPR 004532:IPR002547:IPR012340:IPR005147:IPR005146; KEGG: jde:Jden_1109 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: D0WN31 Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synt [...]
  
 
 0.676
Arch_1245
NifC-like ABC-type porter; COGs: COG4149 ABC-type molybdate transport system permease component; InterProIPR006469:IPR011867:IPR003439:IPR000515:IPR 003593; KEGG: sgr:SGR_3501 putative ABC transporter ATPase and permease component; PFAM: ABC transporter related; binding-protein-dependent transport systems inner membrane component; SMART: AAA ATPase; SPTR: A7BBD7 Putative uncharacterized protein; TIGRFAM: NifC-like ABC-type porter; molybdate ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter; TIGRFAM: molyb [...]
  
  
 0.598
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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