STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1249COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR003448:IPR001453; KEGG: xce:Xcel_1817 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin biosynthesis MoaE protein; molybdopterin binding domain; SPTR: D0WL91 Molybdopterin converting factor, subunit 2; PFAM: Probable molybdopterin binding domain; MoaE protein; TIGRFAM: molybdenum cofactor synthesis domain. (330 aa)    
Predicted Functional Partners:
Arch_1246
COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: car:cauri_1058 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin cofactor biosynthesis MoaC region; SPTR: A7BBB8 Putative uncharacterized protein; TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
 
 0.999
Arch_1250
thiamineS protein; InterPro IPR016155:IPR012675:IPR003749; KEGG: fre:Franean1_6174 thiamineS protein; PFAM: thiamineS protein; SPTR: D0WL89 Molybdopterin converting factor, subunit 1; PFAM: ThiS family.
 
 
 0.999
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 
 0.986
Arch_1248
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR009036:IPR016040:IPR000594:IPR007901; KEGG: ach:Achl_2496 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: B8HBS3 UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family.
 0.979
Arch_1247
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 
 0.978
Arch_1609
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 
 0.950
Arch_1244
Molybdenum ABC transporter, periplasmic molybdate-binding protein; COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR005950:IPR006059; KEGG: pac:PPA0504 putative molybdate-binding protein precursor; PFAM: extracellular solute-binding protein family 1; SPTR: Q6AAF9 Putative molybdate-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: Substrate binding domain of ABC-type glycine betaine transport system; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein.
 
   
 0.859
Arch_0394
KEGG: bcv:Bcav_2892 hypothetical protein; SPTR: D0WRX4 UBA/THIF-type NAD/FAD binding fold protein.
  
 0.814
Arch_1256
Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterProIPR009010:IPR006311:IPR011888:IPR017909:IPR 006655:IPR019546:IPR006963:IPR006656:IPR006657; KEGG: pac:PPA0517 anaerobic dimethyl sulfoxide reductase chain A; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; Twin-arginine translocation pathway, signal sequence, subgroup; molydopterin dinucleotide-binding region; SPTR: C2BU50 Possible Trimethylamine-N-oxide reductase (Cytochrome c); TIGRFAM: anaerobic dimethy [...]
 
  
 0.743
Arch_1245
NifC-like ABC-type porter; COGs: COG4149 ABC-type molybdate transport system permease component; InterProIPR006469:IPR011867:IPR003439:IPR000515:IPR 003593; KEGG: sgr:SGR_3501 putative ABC transporter ATPase and permease component; PFAM: ABC transporter related; binding-protein-dependent transport systems inner membrane component; SMART: AAA ATPase; SPTR: A7BBD7 Putative uncharacterized protein; TIGRFAM: NifC-like ABC-type porter; molybdate ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; ABC transporter; TIGRFAM: molyb [...]
 
   
 0.734
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.