STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
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Experiments
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[Homology]
Score
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (354 aa)    
Predicted Functional Partners:
Arch_1246
COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: car:cauri_1058 molybdenum cofactor biosynthesis protein; PFAM: molybdopterin cofactor biosynthesis MoaC region; SPTR: A7BBB8 Putative uncharacterized protein; TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
 
 0.999
Arch_1249
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR003448:IPR001453; KEGG: xce:Xcel_1817 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin biosynthesis MoaE protein; molybdopterin binding domain; SPTR: D0WL91 Molybdopterin converting factor, subunit 2; PFAM: Probable molybdopterin binding domain; MoaE protein; TIGRFAM: molybdenum cofactor synthesis domain.
 
 
 0.986
Arch_1250
thiamineS protein; InterPro IPR016155:IPR012675:IPR003749; KEGG: fre:Franean1_6174 thiamineS protein; PFAM: thiamineS protein; SPTR: D0WL89 Molybdopterin converting factor, subunit 1; PFAM: ThiS family.
  
  
 0.912
folE
COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602:IPR001474:IPR018234; KEGG: art:Arth_0152 GTP cyclohydrolase; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: C0W610 GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
    
  0.907
Arch_1247
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.893
Arch_1609
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.887
Arch_1430
COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR009061; KEGG: bcv:Bcav_1154 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; PRIAM: Adenylate cyclase; SPTR: D0WPL7 Putative adenylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain.
   
 0.810
Arch_1707
COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833; KEGG: cdi:DIP0465 anaerobic ribonucleoside triphosphate reductase; SPTR: C0W489 Anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase.
    
 0.810
Arch_0493
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453:IPR008284; KEGG: tfu:Tfu_0376 molybdopterin adenylyltransferase; PFAM: molybdopterin binding domain; SPTR: Q47T03 Molybdopterin adenylyltransferase; PFAM: Probable molybdopterin binding domain.
 
  
 0.806
Arch_0828
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
  0.806
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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