STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arch_1283COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: bcv:Bcav_3034 putative signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: C0W6Q0 Signal transduction histidine kinase; PFAM: PspC domain. (406 aa)    
Predicted Functional Partners:
Arch_1282
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR000792:IPR001789:IPR011991:IPR011006:IPR 016032; KEGG: jde:Jden_0656 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: C7R1A5 Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
 
 
 0.952
Arch_1284
Phage shock protein C, PspC; InterPro IPR007168; KEGG: rsa:RSal33209_0977 putative stress-responsive transcriptional regulator; PFAM: PspC domain protein; SPTR: C0W6P9 Possible phage shock protein C, PspC; PFAM: PspC domain; TIGRFAM: LPXTG-motif cell wall anchor domain.
 
  
 0.941
Arch_1281
Maltose O-acetyltransferase; COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451:IPR011004:IPR018357; KEGG: tfu:Tfu_1260 maltose O-acetyltransferase; SPTR: D0YUJ3 Maltose O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats).
       0.773
Arch_1285
Hypothetical protein; KEGG: chl:Chy400_1644 polysaccharide biosynthesis protein; SPTR: C0W6P8 Putative uncharacterized protein.
       0.534
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.511
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
       0.511
Arch_0415
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR011991:IPR000792:IPR001789:IPR011006:IPR 016032; KEGG: bcv:Bcav_2822 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: D0WS35 Two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
  
 
 0.484
Arch_0526
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR011991:IPR001789:IPR013249:IPR000792:IPR 011006; KEGG: kra:Krad_4263 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; SPTR: D0YQC0 Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
  
 
 0.484
Arch_0529
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterProIPR011991:IPR000792:IPR001789:IPR011006:IPR 016032; KEGG: ckp:ckrop_0504 two-component system, response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: D0WNH1 Two-component system response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
  
 
 0.484
Arch_1078
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR011006:IPR000792:IPR001789:IPR011991; KEGG: jde:Jden_1659 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; SPTR: D0WNC4 DNA-binding response regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
  
 
 0.484
Your Current Organism:
Arcanobacterium haemolyticum
NCBI taxonomy Id: 644284
Other names: A. haemolyticum DSM 20595, Arcanobacterium haemolyticum ATCC 9345, Arcanobacterium haemolyticum CIP 103370, Arcanobacterium haemolyticum DSM 20595, Arcanobacterium haemolyticum str. DSM 20595, Arcanobacterium haemolyticum strain DSM 20595
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.